Claims for Patent: 4,897,389

Summary for Patent: 4,897,389

Title:	Treating central nervous system diseases
Abstract:	A method of treating human suffering from central nervous system diseases, such as Alzheimer\'s disease, Parkinson\'s disease, senile dementia. The treatment consists of inducing into the patient\'s blood stream at least one from the group consisting of: sex hormones and anabolic hormones. Growth hormone is also being used in those patients in advanced stages of the disease, or in those patients where it has been determined that a low level of growth hormone is present. A method of diagnosing Alzheimer\'s disease, senile dementia, by the determination of the levels of the hormones somatotropin (human growth hormone) and somatomedin-C (IGF-I) after the administration of the Aroonsakul-Allen provocative test is also disclosed. Blood-sera samples are taken at certain time periods after the administration of L-Dopa, and the samples are tested for the levels of these hormones. These levels are then compared against the levels for normal subjects.
Inventor(s):	Aroonsakul; Chaovanee (Chicago, IL)
Assignee:
Application Number:	07/293,134
Patent Claims:	1. A method for treating central nervous system diseases in human beings, said diseases selected from Senile Dementia, Parkinson's disease, cerebral atrophy, Alzheimer's disease, cerebellar atrophy, senile tremor, and essential tremor, comprising: inducing into the blood stream of a female human being suffering from the disease an effective dosage of a female estrogenic sex hormone from the group consisting of: estradiol, estrone and estriol. 2. The method according to claim 1, further comprising administering at least one of a gonadotropin and chorionic gonadatropin for the female patient. 3. The method according to claim 2, further comprising inducing into the bloodstream of a female patient suitable dosage from a group consisting of: androgens, anabolic hormones, and androgen-anabolic hormone combinations. 4. The method according to claim 2, further comprising inducing into the bloodstream of a female patient suitable dosage of human growth hormone. 5. The method according to claim 3, wherein said androgens is taken from a group consisting of: testosterone, methyltestosterone, fluoxymesterone, and oxymethone.

Details for Patent 4,897,389

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Ferring Pharmaceuticals Inc.	NOVAREL	chorionic gonadotropin	For Injection	017016	01/15/1974		2007-01-30
Ferring Pharmaceuticals Inc.	NOVAREL	chorionic gonadotropin	For Injection	017016	12/27/1984		2007-01-30
Ferring Pharmaceuticals Inc.	NOVAREL	chorionic gonadotropin	For Injection	017016	02/15/1985		2007-01-30
Ferring Pharmaceuticals Inc.	NOVAREL	chorionic gonadotropin	For Injection	017016	02/16/1990		2007-01-30
Bel-mar Laboratories, Inc.	CHORIONIC GONADOTROPIN	chorionic gonadotropin	Injection	017054	03/26/1974		2007-01-30
Ferring Pharmaceuticals Inc.	A.P.L.	chorionic gonadotropin	For Injection	017055	12/13/1974		2007-01-30
Fresenius Kabi Usa, Llc	CHORIONIC GONADOTROPIN	chorionic gonadotropin	For Injection	017067	03/05/1973		2007-01-30