Last Updated: May 1, 2026

Claims for Patent: 11,124,578


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Summary for Patent: 11,124,578
Title:Method of treating transplant rejection with silent Fc variants of anti-CD40 antibodies
Abstract:The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
Inventor(s):Heusser Christoph, Rush James, Vincent Karen
Assignee:NOVARTIS AG
Application Number:US16399250
Patent Claims:

Details for Patent 11,124,578

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. REMICADE infliximab For Injection 103772 August 24, 1998 ⤷  Start Trial 2039-04-30
Immunex Corporation ENBREL etanercept For Injection 103795 November 02, 1998 ⤷  Start Trial 2039-04-30
Immunex Corporation ENBREL etanercept For Injection 103795 May 27, 1999 ⤷  Start Trial 2039-04-30
Immunex Corporation ENBREL etanercept Injection 103795 September 27, 2004 ⤷  Start Trial 2039-04-30
Immunex Corporation ENBREL etanercept Injection 103795 February 01, 2007 ⤷  Start Trial 2039-04-30
Immunex Corporation ENBREL MINI etanercept Injection 103795 September 14, 2017 ⤷  Start Trial 2039-04-30
Immunex Corporation ENBREL etanercept Injection 103795 ⤷  Start Trial 2039-04-30
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 11,124,578

Country Patent Number Estimated Expiration
South Africa 201302532 ⤷  Start Trial
World Intellectual Property Organization (WIPO) 2012065950 ⤷  Start Trial
Uruguay 39292 ⤷  Start Trial
Uruguay 33728 ⤷  Start Trial
United States of America 9828433 ⤷  Start Trial
United States of America 9688768 ⤷  Start Trial
United States of America 9221913 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration

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