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Last Updated: December 16, 2025

Biologic Drugs With Mechanism of Action: Tumor Necrosis Factor Receptor Blocking Activity

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Biologic Drugs With Mechanism of Action: Tumor Necrosis Factor Receptor Blocking Activity

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Patent Expiration
Janssen Biotech, Inc.	REMICADE	infliximab	For Injection	103772	1998-08-24	⤷ Get Started Free	⤷ Get Started Free
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	⤷ Get Started Free	⤷ Get Started Free
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	5,395,760	⤷ Get Started Free
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	5,605,690	⤷ Get Started Free
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	5,712,155	⤷ Get Started Free
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	5,945,397	⤷ Get Started Free
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	6,201,105	⤷ Get Started Free
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Patent Expiration

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