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Last Updated: March 26, 2026

Biologic Drugs With Mechanism of Action: Tumor Necrosis Factor Receptor Blocking Activity

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Biologic Drugs With Mechanism of Action: Tumor Necrosis Factor Receptor Blocking Activity

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Patent Expiration
Janssen Biotech, Inc.	REMICADE	infliximab	For Injection	103772	1998-08-24	⤷ Start Trial	⤷ Start Trial
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	⤷ Start Trial	⤷ Start Trial
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	⤷ Start Trial	⤷ Start Trial
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	⤷ Start Trial	⤷ Start Trial
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	⤷ Start Trial	⤷ Start Trial
Immunex Corporation	ENBREL	etanercept	For Injection	103795	1998-11-02	⤷ Start Trial	⤷ Start Trial
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Patent Expiration

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