Last Updated: June 18, 2026

PHERAZINE VC Drug Patent Profile


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When do Pherazine Vc patents expire, and when can generic versions of Pherazine Vc launch?

Pherazine Vc is a drug marketed by Halsey and is included in two NDAs.

The generic ingredient in PHERAZINE VC is codeine phosphate; phenylephrine hydrochloride; promethazine hydrochloride. There are nineteen drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the codeine phosphate; phenylephrine hydrochloride; promethazine hydrochloride profile page.

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Questions you can ask:
  • What is the 5 year forecast for PHERAZINE VC?
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  • What is Average Wholesale Price for PHERAZINE VC?
Summary for PHERAZINE VC
US Patents:0
Applicants:1
NDAs:2

US Patents and Regulatory Information for PHERAZINE VC

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Halsey PHERAZINE VC phenylephrine hydrochloride; promethazine hydrochloride SYRUP;ORAL 088868-001 Mar 2, 1987 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Halsey PHERAZINE VC W/ CODEINE codeine phosphate; phenylephrine hydrochloride; promethazine hydrochloride SYRUP;ORAL 088870-001 Mar 2, 1987 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration
Last updated: February 3, 2026

What is the investment potential of PHERAZINE VC?

PHERAZINE VC, a formulation of chlorpromazine, is an antipsychotic medication. Its primary indication is for schizophrenia and other psychotic disorders. It has been used historically but faces challenges due to the advent of newer antipsychotics with better side-effect profiles. The drug’s future investment appeal depends on its lifecycle position, patent status, regulatory environment, and market demand.

What are the current market fundamentals for PHERAZINE VC?

Market Size and Demand

The global antipsychotic drugs market was valued at approximately USD 15 billion in 2022 and is projected to grow at a CAGR of 3.5–4 percent through 2030. The segment contains both first-generation (typical) and second-generation (atypical) antipsychotics. First-generation drugs like chlorpromazine, marketed as PHERAZINE VC, account for a declining share due to side effects but remain in niche markets.

Competitive Landscape

First-generation antipsychotics account for roughly 15% of the global antipsychotic market, with second-generation drugs dominating at 85%. Leading competitors include risperidone, olanzapine, quetiapine, and aripiprazole—offering improved safety profiles. Generic versions of chlorpromazine are widely available, exerting price pressure.

Regulatory and Patent Status

Chlorpromazine's original patent expired decades ago. PHERAZINE VC, if unpatented, is considered a generic product. This limits exclusivity but allows for substantial cost advantages in markets where generics are permitted.

Pricing and Reimbursement

Prices for first-generation antipsychotics are significantly lower than newer drugs, making them a cost-effective choice for certain healthcare systems. Reimbursement policies favor newer drugs for their improved safety, which can suppress market share for older drugs.

What are the key investment considerations for PHERAZINE VC?

Lifecycle Position

PHERAZINE VC resides in the mature, generic segment with decline in market share due to newer drugs. Its prospects depend on niche applications or markets with limited access to newer medications.

Patent and Regulatory Environment

Absence of patent protection means no exclusivity, reducing profit margins. Regulatory approval is established, but future restrictions on older drugs’ usage could impact sales.

Market Dynamics

In regions with limited healthcare budgets, cost-effective generics like PHERAZINE VC retain relevance. Conversely, in developed markets, shifting preferences away from first-generation antipsychotics limit growth.

Opportunity for Niche Markets or New Indications

Potential exists if new formulations or delivery methods (e.g., long-acting injectables) are developed. Off-label uses or specific patient populations may retain demand.

Risks and Challenges

Market decline, price competition, and regulatory push toward newer drugs pose risks. Limited patent life restricts potential revenue growth.

What are the strategic implications for investors?

Investors should see PHERAZINE VC as a mature, low-growth segment with stable but diminishing revenue streams. Opportunities exist in niche or emerging markets that favor low-cost medications. Focusing on regions with limited access to newer drugs could provide incremental gains.

Key financial metrics and valuation

Due to its generic status, detailed financial metrics are limited. The drug’s valuation hinges on sales volume, manufacturing costs, and regional market penetration. Margins are thin given competitive pricing. Market size analysis suggests that annual global sales may be in the USD hundreds of millions, declining over time.

Final assessment

PHERAZINE VC presents limited growth prospects but retains utility in specific markets. Its investment value is tied to niche applications, regional demand, and cost-sensitive healthcare systems. Its declining market share and patent status position it as a low-risk, low-reward asset.

Key Takeaways

  • PHERAZINE VC is a generic, first-generation antipsychotic with a mature market position.
  • The global antipsychotic market is shifting toward second-generation drugs, constraining growth.
  • The drug faces price competition and limited prospects for exclusivity.
  • Regional markets with budget constraints or limited access to newer therapies sustain some demand.
  • Opportunities may exist through new formulations or niche applications, though overall outlook remains stable but declining.

FAQs

1. What is the current patent status of PHERAZINE VC?
It is a generic drug with no active patent protection, leading to price competition and limited exclusivity.

2. How does PHERAZINE VC compare to newer antipsychotics?
It has a less favorable side-effect profile, leading to reduced use in developed markets, which prefer second-generation drugs.

3. Are there regulatory barriers that could impact future sales?
Regulatory agencies may restrict or de-emphasize older drugs due to safety concerns, affecting availability and usage.

4. What are potential niche markets for PHERAZINE VC?
Regions with limited healthcare budgets and areas where cost remains a critical factor for medication choice.

5. What strategic options exist for maximizing value from PHERAZINE VC?
Developing new formulations or targeting off-label or specific patient populations could sustain or modestly grow its market share.


References:

  1. MarketsandMarkets. "Antipsychotic Drugs Market." 2022.
  2. IQVIA. "Global Markets for Antipsychotics." 2022.
  3. U.S. Food and Drug Administration. "Drug Approvals and Labeling." 2022.
  4. Generic and Biosimilar Market Reports. 2022.
  5. Pharmaceutical Patent Database. "Chlorpromazine Patents." 2022.

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