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Serving hundreds of leading biopharmaceutical companies globally:

Cipla
Accenture
Boehringer Ingelheim
Cantor Fitzgerald
Merck
Mallinckrodt
Julphar
AstraZeneca
Colorcon

Generated: April 26, 2018

DrugPatentWatch Database Preview

SYPRINE Drug Profile

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When do Syprine patents expire, and what generic alternatives are available?

Syprine is a drug marketed by Aton and is included in one NDA.

The generic ingredient in SYPRINE is trientine hydrochloride. There are nine drug master file entries for this compound. Three suppliers are listed for this compound. Additional details are available on the trientine hydrochloride profile page.
Drug patent expirations by year for SYPRINE
Pharmacology for SYPRINE
Drug ClassMetal Chelator
Mechanism of ActionMetal Chelating Activity
Medical Subject Heading (MeSH) Categories for SYPRINE
Synonyms for SYPRINE
1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-, dihydrochloride
1,2-Ethanediamine,N1,N2-bis(2-aminoethyl)-, hydrochloride (1:2)
2,2'-Ethylenediiminobis(ethylamine) dihydrochloride
260T014
38260-01-4
AC1L2G5T
AC1Q3AVT
ACMC-1AD6N
AKOS028109579
API0004500
C-49679
C6H20Cl2N4
CCG-213505
CHEBI:9706
CTK8C5369
Cuprid
D00736
D09VOK
DB-049259
DTXSID2057863
EINECS 253-854-3
FT-0639448
HC3NX54582
Laszarin
LS-65337
Metalite
MK 0681
MK-0681
MK-681
N,N'-Bis(2-aminoethyl)-1,2-ethanediamine dihydrochloride
n,n'-bis(2-aminoethyl)ethan-1,2-diamindihydrochlorid
N,N'-bis(2-aminoethyl)ethane-1,2-diamine dihydrochloride
N,N'-Bis(2-aminoethyl)ethylenediamine dihydrochloride
N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine dihydrochloride
OR053760
PubChem21105
SCHEMBL506189
Syprine (TN)
TC-164812
TJA-250
Trien dihydrochloride
Trientine Dihydrochloride
Trientine hydrochloride
Trientine hydrochloride (JP17/USP)
Trientine hydrochloride [USAN]
Trientine Hydrochloride, Pharmaceutical secondary standard; traceable to USP
Trientine hydrochloride, United States Pharmacopeia (USP) Reference Standard
Triethylene tetramine dihydrochloride
Triethylenetetramine 2HCl
Triethylenetetramine dihydrochloride
Triethylenetetramine dihydrochloride, puriss., 2xcryst., >=99.0% (AT)
UNII-HC3NX54582
WYHIICXRPHEJKI-UHFFFAOYSA-N

US Patents and Regulatory Information for SYPRINE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Aton SYPRINE trientine hydrochloride CAPSULE;ORAL 019194-001 Nov 8, 1985 AB RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
Accenture
McKesson
Fuji
QuintilesIMS
Merck
US Army
Citi
Covington

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