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Generated: May 26, 2018

DrugPatentWatch Database Preview

SERPASIL Drug Profile

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Which patents cover Serpasil, and when can generic versions of Serpasil launch?

Serpasil is a drug marketed by Novartis and is included in four NDAs.

The generic ingredient in SERPASIL is hydrochlorothiazide; reserpine. There are thirty-two drug master file entries for this compound. Additional details are available on the hydrochlorothiazide; reserpine profile page.
Summary for SERPASIL
Drug patent expirations by year for SERPASIL
Synonyms for SERPASIL
.gamma.-Serpine
(-)-Reserpine
(1S,2R,3R,4aS,13bR,14aS)-methyl 2,11-dimethoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
(3?,16?,17?,18?,20?)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
(3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16- carboxylic acid methyl ester
(3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
005R091
11,17-Dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)yohimban-16-carboxylic acid methyl ester
1407-38-1
141099-49-2
146088-EP2287158A1
146088-EP2292597A1
3-.beta., 18-.beta.-hydroxy-11,17-.alpha.-dimethoxy-,methyl ester, 3,4,5-trimethoxybenzoate (ester)
3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate (ester)
3-beta,20-alpha-yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-, methyl ester,3,4,5-trimethoxybenzoate (ester)
3,4,5-Trimethoxybenzoyl methyl reserpate
3,5-Trimethoxybenzoyl methyl reserpate
3.beta., 18.beta.-hydroxy-11,17.alpha.-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester) (8CI)
3beta,20alpha-yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate (ester)
3P Reserp
4-25-00-01319 (Beilstein Handbook Reference)
50-55-5
79 more names available
8048-25-7
8B1QWR724A
91098-EP2275420A1
91098-EP2305219A1
AB01562943_01
AB2000152
Abesta
Abicol
ABP000583
AC-13142
AC1L1L3K
ACon1_000086
Adelfan
Adelphin
AI3-50146
AKOS000277559
Alkarau
Alkaserp
Alserin
AN-41564
AOB5791
Apoplon
Apoplon (TN)
Apsical
Ascoserp
Ascoserpina
Austrapine
Banasil
Banisil
BB_NC-1905
BBL028800
BDBM50017712
Benazyl
Benz[g]indolo[2, 1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-3-hydroxy-2,11-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate
Bioserpine
BPBio1_001045
Brinderdin
Briserine
BRN 0102014
Broserpine
BSPBio_000949
BT000982
Butiserpazide-25
C06539
Cam-Ap-Es
Cardioserpin
Carditivo
Carpacil
Carrserp
CAS-50-55-5
Caswell No. 722A
CCG-204168
CCRIS 550
CHEBI:28487
CHEMBL772
Chloroserp-250
Chloroserp-500
Chloroserpin-250
Chloroserpine-500
component of Butiserpazide
component of Metatensin
component of Naquival
component of Regroton
component of Renese R
Crystoserpine
CS-1913
D00197
D0J4JM
Darebon
DB00206
Deserpine
Diupres 250
Diupres 500
Diupres-250
Diupres-500
Diurese-R
Diutensen-R
DivK1c_000012
Dralserp
DSSTox_CID_1237
DSSTox_GSID_21237
DSSTox_RID_76029
DTXSID7021237
Eberpine
Eberspine
Ebserpine
EINECS 200-047-9
Elfanex
Elserpine
Enipresser
ENT 50146
EPA Pesticide Chemical Code 123101
esc aspere
Escaspere
Eserpine
Eskaserp
Eskaserpine
EU-0100073
gammaserpine
Gilucard
GTPL4823
H 520
H.R.-50
Helfoserpin
Hexaplin
Hiposerpil
Hiserpia
HMS1570P11
HMS1920P04
HMS2092G05
HMS2097P11
HMS2234E24
HMS3260O07
HMS500A14
HSDB 213
HY-N0480
Hydrap-ES
Hydro-Fluserpine #1
HYDRO-RESERP
Hydro-Reserpine-25
Hydro-Reserpine-50
HYDRO-SERP "25"
HYDRO-SERP "50"
HYDROCHLOROTHIAZIDE W/ RESERPINE
Hydromox R
Hydromox-R
Hydropine
Hydropres 25
Hydropres 50
Hydroserp
Hydroserpalan
Hydroserpine #1
Hydroserpine Plus
Hydrosine 25
Hypercal B
Hypersil
Hypersine
Hypertane forte
Hypertensan
IDI1_000012
Idoserp
Idsoserp
Interpina
J10192
KBio1_000012
KBio2_000549
KBio2_003117
KBio2_005685
KBio3_001808
KBioGR_001397
KBioSS_000549
Key-serpine
Kitine
Klimanosid
KS-5106
l -Carpserp
l-Carpserp
l"-Carpserp
Lemiserp
Lopac0_000073
loweser p
Loweserp
LP00073
LS-1306
Mallopress
Marnitension simple
Maviserpin
Mayserpine
MCULE-9131256292
MCULE-9946449258
MEGxp0_001904
Mephaserpin
Metatensin #2
Metatensin #4
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
METHYL (1R,15S,17R,18R,19S,20S)-6,18-DIMETHOXY-17-(3,4,5-TRIMETHOXYBENZOYLOXY)-3,13-DIAZAPENTACYCLO[11.8.0.0(2),(1)?.0?,?.0(1)?,(2)?]HENICOSA-2(10),4,6,8-TETRAENE-19-CARBOXYLATE
METHYL (1R,15S,17R,18R,19S,20S)-6,18-DIMETHOXY-17-(3,4,5-TRIMETHOXYBENZOYLOXY)-3,13-DIAZAPENTACYCLO[11.8.0.0(2),(1)?.0?,?.0(1)?,(2)?]HENICOSA-2(10),4(9),5,7-TETRAENE-19-CARBOXYLATE
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[(3,4,5-trimethoxyphenyl)carbonyloxy]-3,13-diazapentacyclo[11.8.0.0;{2,10}.0;{4,9}.0;{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
methyl (1S,2R,3R,4aS,13bR,14aS)-2,11-dimethoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-bis(methyloxy)-18-({[3,4,5-tris(methyloxy)phenyl]carbonyl}oxy)yohimban-16-carboxylate
methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-{[(3,4,5-trimethoxyphenyl)carbonyl]oxy}yohimban-16-carboxylate
methyl 11,17alpha-dimethoxy-18beta-(3,4,5-trimethoxybenzoyloxy)-3beta,20alpha-yohimbane-16beta-carboxylate
Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate 3,4,5-trimethoxybenzoate (ester)
methyl dimethoxy-(3,4,5-trimethoxybenzoyl)oxy-[?]carboxylate
methyl o-(3,4,5-trimethoxybenzo yl)reserpate
methyl o-(3,4,5-trimethoxybenzoyl)reserpate
Methyl reserpate 3,4,5-trimethoxybenzoate (ester)
Methyl reserpate 3,4,5-trimethoxybenzoic acid ester
Methyl reserpate 3,5-trimethoxybenzoic acid ester
Methyl reserpate 3,5-trimethyloxybenzoic acid
Methyl reserpate; 3,4,5-Trimethoxybenzoic acid ester
Methylreserpate 3,4,5-trimethoxybenzoic acid
Methylreserpate 3,4,5-Trimethoxybenzoic acid ester
MFCD00005091
MLS002154046
MLS006011754
Modenol
MolPort-000-881-944
Naquival
NCGC00091250-01
NCGC00091250-02
NCGC00091250-03
NCGC00091250-04
NCGC00091250-05
NCGC00091250-06
NCGC00091250-07
NCGC00091250-08
NCGC00091250-09
NCGC00091250-10
NCGC00091250-12
NCGC00254489-01
NCGC00259944-01
NCGC00260758-01
NCI-C50157
NCI60_004446
nembuserpin
Neo-antitensol
neo-serp
neose rfin
Neoserfin
Neoserp
Neoslowten
NINDS_000012
Novoreserpine
NSC 237659
NSC-237659
NSC-59272
NSC-757309
NSC237659
NSC59272
NSC757309
Orthoserpina
Perskleran
Pharmakon1600-01500526
PL000459
PL011018
Pressimedin
Prestwick_147
Prestwick0_000875
Prestwick1_000875
Prestwick2_000875
Prestwick3_000875
Purserpine
Q-100566
QEVHRUUCFGRFIF-MDEJGZGSSA-N
Quiescin
R 0875
R-e-s
rau sedyl
Rau-Sed
Raucap
Raudiford
Raudixin
Raudixoid
Raugal
Raulen
Rauloydin
Raumorine
Raunervil
Raunorine
Raunova
Raupasil
Raupoid
Raurine
Rausan
Rausedan
Rausedil
Rausedyl
Rauserpin
Rauserpin-Alk
Rauserpine
Rauserpol
Rausingle
Rautrin
Rauvlid
Rauwasedin
Rauwilid
Rauwiloid
Rauwipur
Rauwita
Rauwoleaf
Rawilid
RCRA waste no. U200
Rcra waste number U200
Recipin
Regroton
Renese R
Renese-R
Resaltex
rese rpamed
Rese-lar
Resedrex
Resedril
Reser-ar
Reserbal
Resercaps
Resercen
Reserfia
Reserjen
Reserlor
Reserp
Reserpal
Reserpamed
Reserpanca
Reserpene
Reserpex
Reserpic acid methyl ester 3,4,5-trimethoxybenzoate (ester)
Reserpidefe
Reserpil
Reserpin
Reserpina
Reserpina [INN-Spanish]
reserpine
Reserpine (JP17/USP/INN)
Reserpine [USAN:INN:BAN:JAN]
Reserpine [USP:INN:BAN:JAN]
RESERPINE AND HYDROCHLOROTHIAZIDE
RESERPINE AND HYDROCHLOROTHIAZIDE-50
Reserpine solution, 1 pg/muL in methanol: water (1:1)
Reserpine Standard for LC-MS, analytical standard, for LC-MS
Reserpine, 99%
Reserpine, certified reference material, TraceCERT(R)
Reserpine, crystallized, >=99.0% (HPLC)
Reserpine, European Pharmacopoeia (EP) Reference Standard
Reserpine, pharmaceutical secondary standard; traceable to USP, PhEur
Reserpine, United States Pharmacopeia (USP) Reference Standard
Reserpine, Vetec(TM) reagent grade
Reserpine/
Reserpinum
Reserpka
Reserpoid
Reserpur
Reserutin
Resiatric
Residin
Residine
Resine
Resocalm
Resperin
Resperine
Respital
Restran
Rezerpin
Riserpa
Rivased
Rivasin
Rolserp
Roxel
Roxinoid
Roxynoid
Ryser
Salupres
Salutensin
Salutensin-Demi
Sandril
Sandron
SBI-0050061.P004
SC-18569
SCHEMBL2589
se rpate
Sedaraupin
Sedaraupina
Sederaupin
Sedserp
Seominal
Ser-A-Gen
Serfin
Serfolia
Serolfia
Serp-AFD
Serpalan
Serpalan (TN)
Serpaloid
Serpaneurona
Serpanray
Serpasil premix
Serpasil-apresoline
Serpasil-Esidrix #1
Serpasil-Esidrix #2
Serpasol
Serpate
Serpazil
Serpazol
Serpedin
Serpen
Serpena
Serpentil
Serpentin
Serpentina
Serpicon
Serpil
Serpiloid
Serpilum
Serpine
Serpine (pharmaceutical)
Serpipur
Serpivate
Serpivite
Serpogen
Serpoid
Serpone
Serpyrit
Sertabs
Sertens
Sertensin
Sertina
SK-Reserpine
SMR000059122
Solfo serpine
SPBio_002870
Spectrum_000109
SPECTRUM1500526
Spectrum3_000894
Spectrum4_000989
Spectrum5_001415
STK801975
Supergan
T-Serp
Tefaserpina
Tempo-Reserpina
Temposerpine
Tensanyl
Tenserpinie
Tensional
Tensionorme
Tepserpine
Terbolan
Tox21_111107
Tox21_111107_1
Tox21_202395
Tox21_300537
Tox21_500073
Transerpin
Trimethoxybenzoyl methyl reserpate
Triserpin
Tylandril
UNII-8B1QWR724A
Unilord
UNM000011053801
Usaf cb-27
V Serp
V-Serp
Veriloid
VI XO
Vio-Serpine
VIXO
WLN: T F6 D5 C666 EM ON&&TTTJ HO1 SOVR CO1 DO1 EO1& TO1 UVO1
yohimban-16-carboxylic acid derivative of benz[g]indolo[2,3-a]quinolizine
Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
Yohimban-16-carboxylic acid,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-
ZINC3938746

US Patents and Regulatory Information for SERPASIL

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Novartis SERPASIL reserpine ELIXIR;ORAL 009115-005 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Novartis SERPASIL-APRESOLINE hydralazine hydrochloride; reserpine TABLET;ORAL 009296-002 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Novartis SERPASIL reserpine TABLET;ORAL 009115-003 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Novartis SERPASIL-ESIDRIX #1 hydrochlorothiazide; reserpine TABLET;ORAL 011878-003 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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