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US Army
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Generated: May 23, 2018

DrugPatentWatch Database Preview

PRIMAXIN Drug Profile

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When do Primaxin patents expire, and when can generic versions of Primaxin launch?

Primaxin is a drug marketed by Merck and is included in three NDAs.

The generic ingredient in PRIMAXIN is cilastatin sodium; imipenem. There are sixteen drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the cilastatin sodium; imipenem profile page.
Drug patent expirations by year for PRIMAXIN
Pharmacology for PRIMAXIN
Synonyms for PRIMAXIN
(5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
(5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid monohydrate
(5R,6S)-3-((2-formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
(5R,6S)-3-({2-[(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-3-[2-(aminomethyleneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
(5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure
(5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid--water (1/1)
(5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-6-[(1R)-1-hydroxyethyl]-3-(2-methanimidamidoethylsulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate
(6 R,7 R)-7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID monohydrate
[5R-[5.alpha.,6.alpha.(R*)]]-6-(1-Hydroxyethyl)-3-[[2- [(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2- ene-2-carboxylic acid monohydrate
[5R-[5.alpha.,6.alpha.(R*)]]-6-(1-Hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate
1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-((1R)-1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R,6S)-
1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5-alpha,6-alpha(R*)))-
1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, monohydrate, (5R-(5alpha,6alpha(R*)))-
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-
103730-39-8
127644-14-8
221I869
345631-68-7
64221-86-9
64221-86-9 (ANHYDROUS)
64221-86-9 (Parent)
71OTZ9ZE0A
74431-23-5
75902-88-4
847I667
AB0019764
AB01563339_01
AC-15445
AC1L2XLB
AC1NQZYV
AJ-47996
AK115957
AK118710
AKOS015962000
AKOS016010844
Ambap64221-86-9
AN-15734
AN-9651
BC209124
BDBM50049708
BIDD:GT0686
BPBio1_000525
BSPBio_000477
C06665
C12H17N3O4S.H2O
CAS-64221-86-9
CCG-213597
CCG-220519
CCG-221583
CHEBI:471744
CHEBI:51799
CHEMBL148
CHEMBL43708
CS-W019618
D00206
D04515
D0H3TD
DB01598
DR001177
DSSTox_CID_3143
DSSTox_GSID_23143
DSSTox_RID_76888
DTXSID2023143
EINECS 264-734-5
Epitope ID:120384
FT-0627191
FT-0670317
GSOSVVULSKVSLQ-JJVRHELESA-N
HMS1569H19
HMS2090A15
HMS2096H19
HMS3260H20
Imipemide
imipenem
Imipenem (INN)
Imipenem (monohydrate)
Imipenem (USP)
Imipenem [USAN:USP:INN:BAN:JAN]
Imipenem anhydrous
Imipenem hydrate
Imipenem hydrate (JP17)
Imipenem intermediate
Imipenem monohydrate
Imipenem monohydrate, >=98% (HPLC)
Imipenem monohydrate, United States Pharmacopeia (USP) Reference Standard
Imipenem-1-wasser
Imipenem, Antibiotic for Culture Media Use Only
Imipenem, Monohydrate
Imipenem, N-Formimidoyl thienamycin
Imipenem, pharmaceutical secondary standard; traceable to USP, PhEur
Imipenemum
Imipenemum [Latin]
Imipenen
J10088
LP00279
LP101926
MFCD09753321
MK 0787
MK-0787
MK-787
MolPort-005-935-372
MP-0613
N-formimidoyl thienamycin
N-formimidoyl thienamycin monohydrate
N-Formimidoylthienamycin
NCGC00016928-01
NCGC00167958-01
NCGC00167958-02
NCGC00167958-03
NCGC00167958-05
NCGC00260964-01
NSC-717864
NSC-759901
NSC717864
NSC759901
p-Nitrobenzyl -2- -6-( carbapen-2-em-3-carboxylate
Pharmakon1600-01506001
Prestwick_844
Prestwick0_000519
Prestwick1_000519
Prestwick2_000519
Prestwick3_000519
Primaxin (TN)
Primaxin monohydrate
Primaxin monohydrate|||Tienam monohydrate|||(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate
Q-101423
Q20IM7HE75
RL04827
SCHEMBL1649260
SCHEMBL5980
SCHEMBL8781920
SPBio_002398
SR-05000000294
SR-05000000294-3
SR-05000000294-5
ST24020641
Tienam monohydrate
Tienamycin
Tox21_110689
Tox21_110689_1
Tox21_500279
UNII-71OTZ9ZE0A
UNII-Q20IM7HE75
V0250
X-2302
ZINC4097225
ZSKVGTPCRGIANV-ZXFLCMHBSA-N

US Patents and Regulatory Information for PRIMAXIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Merck PRIMAXIN cilastatin sodium; imipenem INJECTABLE;INJECTION 062756-001 Jan 8, 1987 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Merck PRIMAXIN cilastatin sodium; imipenem POWDER;INTRAMUSCULAR 050630-002 Dec 14, 1990 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Merck PRIMAXIN cilastatin sodium; imipenem INJECTABLE;INJECTION 062756-002 Jan 8, 1987 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Merck PRIMAXIN cilastatin sodium; imipenem POWDER;INTRAMUSCULAR 050630-001 Dec 14, 1990 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for PRIMAXIN

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Merck PRIMAXIN cilastatin sodium; imipenem POWDER;INTRAVENOUS 050587-001 Nov 26, 1985 ➤ Try a Free Trial ➤ Try a Free Trial
Merck PRIMAXIN cilastatin sodium; imipenem POWDER;INTRAMUSCULAR 050630-001 Dec 14, 1990 ➤ Try a Free Trial ➤ Try a Free Trial
Merck PRIMAXIN cilastatin sodium; imipenem POWDER;INTRAVENOUS 050587-002 Nov 26, 1985 ➤ Try a Free Trial ➤ Try a Free Trial
Merck PRIMAXIN cilastatin sodium; imipenem POWDER;INTRAMUSCULAR 050630-002 Dec 14, 1990 ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Chubb
Healthtrust
Boehringer Ingelheim
Mallinckrodt
Argus Health
QuintilesIMS
Fuji
Federal Trade Commission
Fish and Richardson

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