Last Updated: May 12, 2026

POTASSIUM CHLORIDE 0.075% IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER Drug Patent Profile


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When do Potassium Chloride 0.075% In Sodium Chloride 0.9% In Plastic Container patents expire, and what generic alternatives are available?

Potassium Chloride 0.075% In Sodium Chloride 0.9% In Plastic Container is a drug marketed by B Braun and is included in one NDA.

The generic ingredient in POTASSIUM CHLORIDE 0.075% IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER is potassium chloride; sodium chloride. There are two hundred and forty drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the potassium chloride; sodium chloride profile page.

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Summary for POTASSIUM CHLORIDE 0.075% IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
Pharmacology for POTASSIUM CHLORIDE 0.075% IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER

US Patents and Regulatory Information for POTASSIUM CHLORIDE 0.075% IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
B Braun POTASSIUM CHLORIDE 0.075% IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER potassium chloride; sodium chloride INJECTABLE;INJECTION 019708-002 Sep 29, 1989 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for Potassium Chloride 0.075% in Sodium Chloride 0.9% in Plastic Container

Last updated: April 26, 2026

What is the product’s market lane and demand driver profile?

Potassium Chloride 0.075% in Sodium Chloride 0.9% in plastic container is a compounded or distributor-supplied intravenous (IV) electrolyte solution used to correct or prevent electrolyte abnormalities, most commonly hypokalemia, in hospital and acuity-driven settings. Its demand is tied to:

  • Inpatient acuity volumes (ED to ward transitions, surgery, ICU utilization)
  • Electrolyte monitoring and correction protocols (standard-of-care pathways in hospitals)
  • Hospital formulary behavior (standard stocking SKUs vs pharmacy compounding)
  • Procurement and supply continuity (substitution risk and logistics for IV fluids)
  • Regulatory and safety expectations around container integrity and sterility assurance for IV administration.

The core commercial reality for IV solutions is that volume is largely institutional. The product’s “market” is less about outpatient adoption and more about contracts, stocking decisions, and pharmacy procurement cycles. In practice, the competitive set includes:

  • Same-nutrient electrolyte premixes in IV saline backgrounds
  • Alternative potassium concentration strengths
  • Potassium chloride additives compounded into compatible IV fluids
  • Therapeutically adjacent regimens (potassium supplementation routes that displace IV use when clinically feasible)

How does pricing and contracting typically evolve in this segment?

Pricing for IV premixes and electrolyte solutions is shaped by three levers:

  1. Contract mechanics drive realized pricing

    • Hospitals buy through group purchasing organizations, GPO-negotiated contracts, and direct distributor tenders.
    • Realized price tends to move with contract renewals and bid cycles rather than on-the-fly list-price changes.
  2. Input cost volatility is usually moderate but can be destabilizing

    • Sodium chloride and potassium chloride are bulk commodities; cost swings can pass through when supply tightens.
    • Transportation and packaging costs (notably container format) can create step-changes even when commodity costs are stable.
  3. Container and supply assurance create SKU stickiness

    • “Plastic container” is a material differentiator versus vial or bag formats in some procurement portfolios.
    • Institutions prefer continuity and compatibility for workflow and nursing administration.

Commercial implication: the product typically experiences stable-to-slow pricing growth with periodic dips or spikes around supply shocks and contract renewals, rather than sustained premium pricing.

What competitive dynamics determine share retention?

This product’s defensibility is functional, not patent-like. Key competitive dynamics:

  • Therapeutic substitutability

    • Clinicians choose based on potassium target dose, infusion compatibility, and protocol endpoints.
    • If lower/higher potassium strengths are stocked more broadly, this SKU can lose share without clinical differentiation.
  • Supply reliability

    • IV electrolyte shortages shift hospital allocations to whichever SKU arrives reliably.
    • Once a hospital establishes a supply pattern, switching can require revalidation in pharmacy workflows.
  • Formulary placement and stocking strategy

    • Hospitals often stock a small set of standardized electrolyte solutions to minimize inventory complexity.
    • If this strength is not in the standardized formulary set, usage can be episodic.
  • Compounding displacement

    • Some systems compound potassium into compatible saline backgrounds, especially when premixed SKUs are scarce.
    • Where premixes are plentiful and contract pricing is competitive, compounded displacement reverses.

Commercial implication: share retention depends on distribution reliability and contract placement more than on clinical differentiation.

What is the financial trajectory profile for this type of IV electrolyte solution?

For hospital IV electrolyte products with commodity components and institutional demand, the financial trajectory typically follows an “install-and-renew” curve:

Trajectory shape (typical pattern)

  • Initial phase: sales ramp depends on formulary inclusion, conversion from compounding, and distributor reach.
  • Stabilization: once a hospital standardizes the SKU, usage becomes steady and tied to patient volume.
  • Maturity: growth tracks inpatient volumes and contract-driven price adjustments.
  • Merging or displacement: share erosion occurs if competing strengths become the stocked default or if shortages shift allocation.

Revenue growth drivers

  • Increases in hospital admissions, surgery volumes, and ICU utilization
  • Conversion of compounded potassium into premixed electrolyte products
  • Broader distributor coverage and GPO inclusion
  • Contract renewals at stable or improved net prices

Revenue headwinds

  • Loss of formulary status or substitution to other potassium concentrations
  • Contract pricing pressure during competitive bidding
  • IV fluid supply normalization if shortages previously favored premixed electrolytes
  • Shifts in clinical protocols to alternative supplementation routes

Margin structure (institutional IV products)

  • Gross margins are compressed by commodity-based inputs and competitive tendering.
  • Operating margins depend on logistics efficiency, contract terms, and working capital management.
  • Inventory risk is meaningful because IV products have shelf-life constraints; distributor and manufacturer forecasts heavily influence margin.

Commercial implication: unless the SKU is protected by supply constraints or embedded as a default premix within large contract frameworks, financial performance tends to be volume-led with modest pricing-led growth.

How do market shocks and policy factors translate into near-term financial outcomes?

Supply-chain shocks

  • Container availability constraints can cause temporary reallocation, lifting short-term sales for available suppliers.
  • Raw material or manufacturing disruptions can shift demand toward available premixed alternatives.

Demand shocks

  • Increased acute care admissions can raise electrolyte correction volumes.
  • Seasonal patterns can affect hospital acuity but are secondary to inpatient volume.

Policy and procurement behavior

  • Drug procurement standardization across systems can consolidate purchases into preferred SKUs, improving predictability for winners.
  • Budget pressure can intensify tender competition, pulling net pricing down at renewal.

Financial translation: in this category, near-term revenue volatility often stems more from contract timing and supply continuity than from demand shifts for the active ingredient alone.

What benchmarks should investors and operators use to track financial trajectory?

Because this product is contract-driven, the best financial indicators are operational rather than marketing metrics:

  • GPO and IDN coverage: number of large hospital systems ordering this SKU under contract
  • Net price trend at contract renewal: not list price
  • Unit volumes: dispensed units or cases shipped, segmented by customer type (acute care, surgery centers, integrated delivery networks)
  • Backorder and fill-rate metrics: shortages can temporarily lift sales for available producers but can also create long-term churn if reliability fails
  • SKU mix: share of 0.075% potassium strength versus other potassium strengths in the same saline background
  • Compounding displacement rate: whether hospitals keep premixed electrolyte stock or shift back to compounded additions

Key Takeaways

  • The product’s market is institutional and driven by inpatient acuity, electrolyte protocols, and hospital contracting cycles.
  • Pricing behavior is typically contract-driven with stability punctuated by tender renegotiations and supply shocks.
  • Financial trajectory follows a ramp-to-stability curve tied to formulary inclusion, distributor reach, and supply continuity, with modest price-led growth and volume-led performance.
  • Competition is functional and substitute-heavy (other potassium strengths and compounded alternatives), so share depends on formulary positioning and reliability.
  • Near-term revenue variability is more likely to come from contracting timing and supply availability than from fundamental demand changes for potassium itself.

FAQs

1) Is this product typically a patent-protected growth engine?

No. Its market dynamics align with institutional IV electrolyte premix procurement, where share depends on formulary and supply chain inclusion rather than long-lived exclusivity economics.

2) What most strongly influences hospital utilization?

Inpatient volume and clinical protocols that govern potassium correction and monitoring, paired with whether the hospital stocks this exact strength and container format.

3) Do container format decisions affect sales?

Yes. Plastic container compatibility and availability can affect purchasing decisions, replacement behavior, and continuity of administration workflows.

4) What determines whether the product grows or erodes over time?

Whether the SKU becomes a default contract item for electrolyte premixing versus being displaced by other potassium strengths or compounded potassium additions.

5) What is the best leading indicator for financial trajectory?

Net contract pricing plus shipped unit volumes at major IDNs and GPO-covered customers, supported by fill-rate and backorder history.


References

  1. FDA. Drug Shortages. https://www.accessdata.fda.gov/scripts/drugshortages/ (accessed 2026-04-26)

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