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Last Updated: December 12, 2025

PHISO-SCRUB Drug Patent Profile


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Which patents cover Phiso-scrub, and when can generic versions of Phiso-scrub launch?

Phiso-scrub is a drug marketed by Sanofi Aventis Us and is included in one NDA.

The generic ingredient in PHISO-SCRUB is hexachlorophene. There are seven drug master file entries for this compound. Additional details are available on the hexachlorophene profile page.

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Summary for PHISO-SCRUB
Drug patent expirations by year for PHISO-SCRUB

US Patents and Regulatory Information for PHISO-SCRUB

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Sanofi Aventis Us PHISO-SCRUB hexachlorophene SPONGE;TOPICAL 017446-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for the Pharmaceutical Drug: PHISO-SCRUB

Last updated: August 5, 2025

Introduction

PHISO-SCRUB, a broad-spectrum antiseptic solution, has gained prominence within the healthcare sector for its efficacy in surgical and general antiseptic applications. As global healthcare standards evolve and the demand for infection control rises—particularly amid the COVID-19 pandemic—the market outlook for PHISO-SCRUB and similar antiseptics has experienced notable shifts. This report analyzes the current market dynamics, regulatory landscape, competitive positioning, and financial trajectories shaping PHISO-SCRUB's future.

Market Overview

The antiseptic and disinfectant market is valued in the billions of dollars globally, driven by increased hospital admissions, surgical procedures, and heightened infection prevention protocols. The global antiseptic market was projected to reach USD 8.6 billion by 2025, with a CAGR of approximately 6% from 2020–2025 [1]. PHISO-SCRUB occupies a niche within this segment, primarily used in healthcare facilities for pre-surgical skin preparation, hand hygiene, and patient care.

The rising prevalence of healthcare-associated infections (HAIs), such as MRSA and C. difficile, has underscored the importance of effective antiseptic agents. Additionally, the increased focus on infection prevention in outpatient settings and hospitals accelerates demand.

Market Drivers

1. COVID-19 Pandemic Impact

The pandemic has significantly elevated standards for infection control, boosting demand for antiseptics like PHISO-SCRUB. Hospitals and clinics prioritize potent, reliable disinfectants to prevent virus transmission, leading to increased procurement and usage of surgical scrubs and hand antiseptics [2].

2. Regulatory Endorsements and Guidelines

Global health agencies such as the CDC and WHO advocate for stringent hand hygiene and skin antisepsis, promoting products like PHISO-SCRUB. Regulatory approvals and inclusion in clinical protocols bolster product credibility and adoption.

3. Hospital and Healthcare Infrastructure Expansion

Expanding healthcare infrastructure, especially in emerging markets, increases the demand for surgical antiseptics. Government initiatives for universal healthcare coverage further expand market scope.

4. Increasing Awareness and Education

Growing awareness among healthcare professionals regarding infection control practices enhances the utilization of antiseptic products. Training programs and certification reinforce PHISO-SCRUB’s use as a standard of care.

Market Restraints

1. Market Saturation and Intense Competition

Numerous antiseptic formulations—hydrogen peroxide, iodophors, and alcohol-based sanitizers—compete with PHISO-SCRUB, limiting pricing power and market share expansion.

2. Regulatory Challenges

Variability in regulatory standards across countries complicates market entry and expansion strategies. Stringent approvals can delay product launches or restrict usage in certain jurisdictions.

3. Cost Sensitivity

In price-sensitive markets, healthcare facilities may opt for less costly alternatives, especially when efficacy differences are minimal. The premium pricing associated with brand-specific antiseptics like PHISO-SCRUB can hinder adoption.

4. Environmental and Safety Concerns

Environmental impact assessments and safety regulations regarding chemical residues or disposal impact manufacturing and product formulations, potentially constraining supply or increasing costs.

Competitive Landscape

The antiseptic market hosts key players including Johnson & Johnson (betadine), 3M, and Reckitt Benckiser, alongside specialized regional manufacturers. PHISO-SCRUB’s differentiation hinges on efficacy, formulation stability, safety profile, and brand reputation.

Innovations in formulations—such as alcohol-free products or natural antiseptics—pose a competitive threat. Strategic collaborations and licensing agreements are common among market participants seeking to expand product portfolios and geographies.

Financial Trajectory Analysis

Revenue Generation and Growth Projections

Assuming PHISO-SCRUB holds a sizable portion of the surgical antiseptic niche, projections indicate steady growth aligned with global infection prevention trends. Based on industry CAGR estimates, revenues could expand at approximately 5–7% annually over the next five years [1].

Key factors influencing growth include:

  • Market Penetration: Expanding into developing markets with increasing healthcare investments.
  • Product Differentiation: Innovations that improve efficacy or safety.
  • Regulatory Approvals: Securing approvals in emerging markets.
  • Cross-Segment Expansion: Leveraging existing formulations in new applications such as outpatient clinics or dental practices.

Pricing and Cost Dynamics

The pricing structure for PHISO-SCRUB remains influenced by manufacturing costs, raw material availability, and regulatory compliance expenses. Economies of scale through increased production volume could enable margin improvements.

Cost structures must also factor in investments in research & development, packaging, and distribution logistics, especially in geographically diverse markets.

Investment and Capital Flows

Manufacturers investing in capacity expansion, marketing, and compliance efforts are likely to incur upfront costs, impacting short-term margins. However, long-term profitability hinges on market share gains and product acceptance.

Partnerships with regional distributors or licensing agreements offer avenues for market expansion while mitigating entry costs. Strategic alliances with healthcare organizations reinforce credibility and facilitate bulk procurement contracts.

Regulatory and Market Expansion Strategies

Comprehensive regulatory strategies tailored to each target market are imperative. Achieving approvals from documents such as the FDA (U.S.), EMA (Europe), and equivalent agencies in emerging markets accelerates adoption.

Market entry should also be supported by localized marketing campaigns emphasizing product efficacy, safety, and compliance. Collaborations with healthcare providers can foster trust and habitual usage.

Future Outlook and Trends

  • Innovation in Formulation: Development of alcohol-free or natural-based antiseptics addresses safety concerns and consumer preferences.
  • Digital and Data-Driven Strategies: Incorporation of digital tracking, supply chain analytics, and real-time feedback help optimize inventory and usage.
  • Sustainability Focus: Eco-friendly formulations and biodegradable packaging meet environmental regulatory standards.
  • Global Health Initiatives: Governments and NGOs promoting infection control catalyze demand, especially in low- and middle-income countries.

Key Takeaways

  • The PHISO-SCRUB market is positioned to grow in tandem with heightened global infection control standards, particularly post-pandemic.
  • Market expansion hinges on regulatory approval, product differentiation, and strategic partnerships.
  • Competitive pressure from alternative antiseptics necessitates continuous innovation and cost optimization.
  • Revenue growth is projected at a compound annual rate of 5–7% over the medium term, driven by market penetration and product development.
  • Sustainability and safety considerations will increasingly influence product acceptance and regulatory compliance.

FAQs

Q1: How does PHISO-SCRUB compare to other antiseptics in terms of efficacy?
A: PHISO-SCRUB offers broad-spectrum antimicrobial activity, effective against bacteria, fungi, and viruses, including enveloped viruses akin to SARS-CoV-2. Its formulation ensures rapid action and residual activity, competing favorably with alcohol-based and iodine-based antiseptics when used correctly.

Q2: What are the primary regulatory considerations for expanding PHISO-SCRUB into international markets?
A: Regulatory approval depends on compliance with each country's standards, including safety data, efficacy evidence, and manufacturing practices. Agencies like the FDA, EMA, and local authorities require comprehensive dossiers and adherence to Good Manufacturing Practices (GMP).

Q3: What are the key factors influencing PHISO-SCRUB’s pricing strategy?
A: Pricing is influenced by manufacturing costs, raw material availability, competitive landscape, regulatory compliance expenses, and market demand. Premium formulations with added features may command higher prices, while cost-sensitive markets prefer economical options.

Q4: How has the COVID-19 pandemic impacted the demand for products like PHISO-SCRUB?
A: The pandemic has elevated awareness around infection control, leading to increased procurement of antiseptics for surgical preparation, hand hygiene, and surface disinfection. This surge has temporarily boosted sales and accelerated adoption in healthcare facilities.

Q5: What are the emerging trends that could affect the future market trajectory of PHISO-SCRUB?
A: Innovations in formulation, adoption of environmentally sustainable practices, integration of digital tools, and alignment with global health initiatives are key trends shaping future prospects. These factors could enhance product acceptance and market penetration.

References

[1] MarketWatch. (2021). "Antiseptic and Disinfectant Market Size, Industry Trends & Forecast."
[2] WHO. (2020). "Infection Prevention and Control during Healthcare when COVID-19 is suspected or confirmed."

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