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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Federal Trade Commission
McKinsey
Fuji
Argus Health
Moodys
AstraZeneca
Chubb
Colorcon

Generated: April 20, 2018

DrugPatentWatch Database Preview

MATULANE Drug Profile

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Which patents cover Matulane, and what generic alternatives are available?

Matulane is a drug marketed by Leadiant Biosci Inc and is included in one NDA.

The generic ingredient in MATULANE is procarbazine hydrochloride. There are four drug master file entries for this compound. Two suppliers are listed for this compound. Additional details are available on the procarbazine hydrochloride profile page.
Drug patent expirations by year for MATULANE
Pharmacology for MATULANE
Drug ClassAlkylating Drug
Mechanism of ActionAlkylating Activity
Medical Subject Heading (MeSH) Categories for MATULANE
Synonyms for MATULANE
1-(p-Isopropylcarbamoylbenzyl)-2-methylhydrazine hydrochloride
1-Methyl-2-(p-isopropylcarbamoylbenzyl)hydrazine hydrochloride
1-methyl-2-p-(isopropylcarbamoyl)benzohydrazide hydrochloride
1-Methyl-2-p-(isopropylcarbamoyl)benzohydrazine hydrochloride
2-(p-(iso propylcarbamoyl)benzyl)-1-methylhydrazine hydrochloride
2-(p-(Isopropylcarbamoyl)benzyl)-1-methylhydrazine hydrochloride
366-70-1
366P701
4-[(2-methyl-hydrazino)-methyl]-benzoic acid isopropylamide hydrochloride
4-[(2-methylhydrazin-1-yl)methyl]-N-(propan-2-yl)benzamide hydrochloride
4-[(2-methylhydrazinyl)methyl]-N-propan-2-yl-benzamide hydrochloride
4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide hydrochloride
4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide;hydrochloride
4-[(methylhydrazo)methyl]-N-propan-2-ylbenzamide hydrochloride
671-16-9 (Parent)
A823326
AB0013275
AB2000412
AC-12163
AC1L1TMP
AI3-50844
AK163571
AKOS015895395
AN-44552
AS-13285
BC204134
BCP0726000264
Benzamide, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)-, monohydrochloride
Benzamide, N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]-, monohydrochloride
C07376
C12H19N3O.HCl
C12H20ClN3O
CAS-366-70-1
CCG-100985
CCRIS 531
CHEBI:71428
CHEMBL1200410
Chlorhydrate de 1-methyl 2 p (isopropylcarbamoyl)benzyl-hydrazine
Chlorhydrate de 1-methyl 2 p (isopropylcarbamoyl)benzyl-hydrazine [French]
CPD000469151
CS-2392
CTK8G2583
D00478
DERJYEZSLHIUKF-UHFFFAOYSA-N
DSSTox_CID_1190
DSSTox_GSID_21190
DSSTox_RID_76000
DTXSID3021190
EINECS 206-678-6
FT-0083574
FT-0603386
H809
HMS1571O06
HY-13733
I06-0654
Ibenzmethyzin hydrochloride
Ibenzmethyzine hydrochloride
IBZ
K-8168
KS-00000XHF
KSC962K8H
LS-96
Matulane (TN)
MBH
MCULE-2203793025
MFCD00072082
MIH hydrochloride
MLS001401414
MolPort-003-849-975
N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide hydrochloride
N-(1-methylethyl)-4-((2-methylhydrazino)methyl)benzamide monohydrochloride
N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide hydrochloride
N-(1-Methylethyl)-4-[(2-methylhydrazinyl)methyl]benzamide hydrochloride
N-isopropyl-4-((2-methylhydrazinyl)methyl)benzamide hydrochloride
N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide hydrochloride
N-isopropyl-alp ha-(2-methylhydrazino)-p-toluamide hydrochloride
N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide hydrochloride
N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide monohydrochloride
N-Isopropyl-p-(2-methylhydrazinomethyl)benzamide hydrochloride
Nathulane
Natulan hydrochloride
Natunalar
NC00235
NCGC00016438-01
NCGC00016438-04
NCGC00255389-01
NCI-C01810
NSC 77213
NSC-77213
NSC77213
OR060554
p-(N'-Methylhydrazinomethyl)-N-isopropylbenzamide hydrochloride
p-Toluamide, monohydrochloride
p-Toluamide, N-isopropyl-alpha-(2-methylhydrazino)-, hydrochloride
p-Toluamide, N-isopropyl-alpha-(2-methylhydrazino)-, monohydrochloride
P2550
PCB hydrochloride
Procarbazine (Hydrochloride)
Procarbazine chloridrate
PROCARBAZINE HCl
Procarbazine hydrochloride
Procarbazine hydrochloride (JP17/USP)
Procarbazine hydrochloride (Matulane)
Procarbazine hydrochloride [USAN:JAN]
Procarbazine hydrochloride, >=98% (HPLC)
Procarbazine hydrochloride, United States Pharmacopeia (USP) Reference Standard
Procarbazine Hydrochloride|||Natulan|||4-[(2-Methylhydrazinyl)methyl]-N-propan-2-ylbenzamide hydrochloride
Procarbazine.HCl
Procarbazinehydrochloride
Ro 4 6467/1
Ro-46467/1
Ro-4646711
s1995
SAM001246564
SBB066151
SCHEMBL4012
SMR000469151
Tox21_110439
Tox21_110439_1
Tox21_302318
UNII-XH0NPH5ZX8
WLN: 1Y1&MVR D1MM1 &GH
XH0NPH5ZX8
Z1550675463

US Patents and Regulatory Information for MATULANE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Leadiant Biosci Inc MATULANE procarbazine hydrochloride CAPSULE;ORAL 016785-001 Approved Prior to Jan 1, 1982 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

QuintilesIMS
Johnson and Johnson
Federal Trade Commission
Cerilliant
Chinese Patent Office
Daiichi Sankyo
Mallinckrodt
Express Scripts
Citi

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