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Generated: April 23, 2018

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ISMELIN Drug Profile

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When do Ismelin patents expire, and what generic alternatives are available?

Ismelin is a drug marketed by Novartis and is included in one NDA.

The generic ingredient in ISMELIN is guanethidine monosulfate. There are two drug master file entries for this compound. Additional details are available on the guanethidine monosulfate profile page.
Drug patent expirations by year for ISMELIN
Medical Subject Heading (MeSH) Categories for ISMELIN
Synonyms for ISMELIN
.Beta.-1-Azacyclooctylethylguanidine
.beta.-1-Azacyclooctylethylguanidine sulfate
((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
(2-(Hexahydro-(2H)-azocin-1-yl)ethyl)guanidinium sulphate
(2-(Hexahydro-1(2H)-azocinyl)ethyl) guanidine hydrogen sulfate
(2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine
(2-(Hexahydro-1(2H)-azocinyl)ethyl)guanidine sulfate (1:1)
(2-(Hexahydro-1(2H)-azocinyl)ethyl)guanidine sulfate (2:1)
(2-(Octahydro-1-azocinyl)ethyl)guanidine
[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine
[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine sulfate
[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine sulfate (2:1)
[2-(Octahydro-1-azocinyl)ethyl]guanidine
[2-(Octahydro-1-azocinyl)ethyl]guanidine sulfate
1-(2-(azocan-1-yl)ethyl)guanidine sulfate
1-(2-azocan-1-ylethyl)guanidine
1-(2-azocan-1-ylethyl)guanidine sulfate
1-[2-(azocan-1-yl)ethyl]guanidine
1-[2-(Azocan-1-yl)ethyl]guanidine (1/2H2SO4)
1-[2-(azocan-1-yl)ethyl]guanidine;sulfuric acid
2-(1-N,N-Heptamethyleneimino)ethylguanidine
2-(1'-Azacyclooctyl)ethylguanidine
2-(2-(azocan-1-yl)ethyl)guanidine
2-(Octahydro-1-azocinyl)ethyl guanidine sulphate
2-[2-(azocan-1-yl)ethyl]guanidine
2-[2-(azocan-1-yl)ethyl]guanidine; sulfuric acid
2450AH
2C10H22N4.H2O4S
3709AH
3h-guanethidine
55-65-2
55-65-2 (Parent)
5UBY8Y002G
60-02-6
60-02-6 (sulfate (2:1))
645-43-2
645-43-2 (sulfate (1:1))
8AQ60474G9
AB00053479
AB00053479_04
AB00053479_05
AB0095438
Abapresin
AC-479
AC1L1G48
AC1L2327
AC1L3BME
ACGDKVXYNVEAGU-UHFFFAOYSA-N
AI3-52043
AK322050
AK322051
AKOS005614041
AKOS015856688
AKOS026750543
AKOS027326528
amino(2-azaperhydroocinylethyl)carboxamidine
AN-15828
AN-23627
API0002870
API0012897
Apo-Guanethidine
Apo-Guanethidine (TN)
Azocine, 1-((2-(aminoiminomethyl)amino)ethyl)octahydro-
Azocine, 1-(2-guanidinoethyl)octahydro-
Azocine, 1-(2-guanidinoethyl)octahydro-, sulfate (2:1)
Azocine, 1-[[2-(aminoiminomethyl)amino]ethyl]octahydro-
Azocine, sulfate (2:1)
BBL005506
BC206571
Beta-1-Azacyclooctylethylguanidine
beta-1-Azacyclooctylethylguanidine sulfate
BPBio1_000346
BSPBio_000314
BSPBio_002092
C07036
C10H22N4
C10H22N4.H2O4S
CAS-60-02-6
CCG-213488
CCG-220317
CCG-39688
CHEBI:51016
CHEBI:51017
CHEBI:5557
CHEMBL1345
CHEMBL2051958
CHEMBL765
CS-3931
CTK8F1339
CTK8G0104
D02237
D04382
D08030
D0N3PE
DB01170
DivK1c_000539
Dopam
Dopom
DR000305
DR003046
DTXSID20110019
DTXSID5023116
EINECS 200-241-3
EINECS 200-452-0
EINECS 211-442-0
EN300-123310
Eutensol
FCH832193
FT-0080899
FT-0603504
FT-0626819
GTPL7194
GUANETHIDINE
Guanethidine (INN)
Guanethidine (sulfate)
Guanethidine [INN:BAN]
Guanethidine bisulfate
Guanethidine Hemisulfate
Guanethidine hemisulphate
Guanethidine monosulfate
Guanethidine monosulfate [USAN:USP]
Guanethidine monosulfate [USAN]
Guanethidine monosulfate, United States Pharmacopeia (USP) Reference Standard
guanethidine monosulphate
guanethidine sulfate
Guanethidine Sulfate (1:1)
Guanethidine Sulfate (2:1)
Guanethidine sulfate (JP17)
Guanethidine sulfate (USAN)
Guanethidine sulfate [USAN:JAN]
Guanethidine sulfate [USAN:USP:JAN]
Guanethidine Sulphae
Guanethidine sulphate
Guanethidinesulfate
Guanethidinum
Guanethidinum [INN-Latin]
Guanetidin sulfate
Guanetidina
Guanetidina [INN-Spanish]
Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-
Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-, sulfate (1:1)
Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-, sulfate (2:1)
Guanidine, (2-(octahydro-1-azocinyl)ethyl)-, hemisulfate
Guanidine, (2-(octahydro-1-azocinyl)ethyl)-, sulfate (2:1)
Guanidine, [2-(hexahydro-1(2H)-azocinyl)ethyl]-
Guanidine, [2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (1:1)
Guanidine, [2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (2:1)
Guanidine, N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-
Guethine
H2793
HE059300
HE352525
HE358508
HE372487
Heptamethylenimine, 1-(2-guanidinoethyl)-
HMS1568P16
HMS1920B19
HMS2091J05
HMS2095P16
HMS501K21
HSDB 3092
HY-B0800
IDI1_000539
Iporal
Iporal (Salt/Mix)
Ismelin (TN)
Ismelin sulfate
Ismelin sulfate (2:1)
ISMELIN; SULFURIC ACID
Isobarin
Isobarin (Salt/Mix)
Isomelin
KBio1_000539
KBio2_001317
KBio2_003885
KBio2_006453
KBio3_001312
KBioGR_000976
KBioSS_001317
KS-0000110Q
L000732
LS-73688
LS-73691
LS-73692
MCULE-1014284503
MCULE-6728556467
MFCD00035403
MFCD00079332
MolPort-001-783-613
MolPort-003-666-197
MolPort-016-580-610
N-(2-Guanidino ethyl)heptamethylenimine sulfate
N-(2-Perhydroazocin-1-ylethyl)guanidine
N-[2-(1-Azocanyl)ethyl]guanidine #
N-[2-(azocan-1-yl)ethyl]guanidine
N-[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine Sulfate
NBJGGHFXCGHTNJ-UHFFFAOYSA-N
NCGC00016272-01
NCGC00016272-02
NCGC00016272-03
NCGC00094691-01
NCGC00094691-02
NCGC00247765-01
NINDS_000539
NSC 29863
NSC-29863
NSC-757045
NSC29863
NSC757045
Octadin
Octadine
Octatensin
Octatensine
Octatenzine
Oktadin
Oktatensin
Oktatenzin
Pharmakon1600-01500323
Prestwick_249
Prestwick0_000317
Prestwick1_000317
Prestwick2_000317
Prestwick3_000317
QC-3179
Sanotensin
SBI-0051399.P003
SCHEMBL11658850
SCHEMBL34753
SCHEMBL51039
SPBio_001206
SPBio_002533
Spectrum_000837
SPECTRUM1500323
Spectrum2_001103
Spectrum3_000446
Spectrum4_000568
Spectrum5_000784
SR-05000001637
SR-05000001637-1
ST012264
ST45025913
ST50819310
STK895063
SU 5864
SU 5864 (Salt/Mix)
Su 5864 sulfate (1:1)
SU-5864
TC-030886
TL8004587
UNII-5UBY8Y002G
UNII-8AQ60474G9
UNII-ZTI6C33Q2Q
W-105285
WLN: T8NTJ A2MYZUM & 2WSQQ
YUFWAVFNITUSHI-UHFFFAOYSA-N
Z2685286029
ZINC1530648
ZTI6C33Q2Q

US Patents and Regulatory Information for ISMELIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Novartis ISMELIN guanethidine monosulfate TABLET;ORAL 012329-001 Approved Prior to Jan 1, 1982 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Novartis ISMELIN guanethidine monosulfate TABLET;ORAL 012329-002 Approved Prior to Jan 1, 1982 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
McKinsey
Citi
Merck
Queensland Health
Baxter
UBS
Chubb
Daiichi Sankyo

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