DrugPatentWatch Database Preview
DEFINITY Drug Profile
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When do Definity patents expire, and when can generic versions of Definity launch?
This drug has forty-two patent family members in thirty countries.
The generic ingredient in DEFINITY is perflutren. One supplier is listed for this compound. Additional details are available on the perflutren profile page.
Summary for DEFINITY
| International Patents: | 42 |
| US Patents: | 4 |
| Applicants: | 1 |
| NDAs: | 1 |
| Suppliers / Packagers: | 1 |
| Bulk Api Vendors: | 34 |
| Clinical Trials: | 41 |
| Patent Applications: | 1,497 |
| Formulation / Manufacturing: | see details |
| DailyMed Link: | DEFINITY at DailyMed |
Pharmacology for DEFINITY
| Drug Class | Contrast Agent for Ultrasound Imaging |
| Mechanism of Action | Ultrasound Contrast Activity |
Synonyms for DEFINITY
| 1,1,1,2,2,3,3,3-Octafluoropropane |
| 1,1,1,2,2,3,3,3-octakis(fluoranyl)propane |
| 218599-63-4 |
| 300408-51-9 |
| 70024-90-7 |
| 76-19-7 |
| A838638 |
| AC1L1MIR |
| AC1Q4IBX |
| AKOS006228213 |
| ALBUMINE HUMAN, ESSENTIALLY FATTY ACID FREE |
| Albumins human |
| AN-23892 |
| AN-37829 |
| C-50894 |
| C3F8 |
| C3F8-gas |
| CHEBI:31980 |
| CHEMBL1663 |
| CK0N3WH0SR |
| CTK5E2580 |
| D01738 |
| D0G5BK |
| DB-056033 |
| DB00556 |
| Definity (TN) |
| DM-115 |
| DMP 115 |
| DMP-115 |
| DTXSID9052503 |
| EINECS 200-941-9 |
| FC 218 |
| FC 218 (refrigerant) |
| FCH918400 |
| Flutec PP30 |
| Freon 218 |
| FS-069 |
| FS-69 |
| FS069 |
| FT-0621948 |
| FT-0631321 |
| Genetron 218 |
| HFC 218 |
| I14-14876 |
| KB-59511 |
| liposome-encapsulated perfluoropane microsphere |
| LS-120891 |
| luminity |
| MFCD00039239 |
| MRX 115 |
| MRX-115 |
| OCTAFLUOROPROPANE |
| OCTAFLUOROPROPANE (FC-218) |
| Octafluoropropane perflutren lipid microsphere |
| octafluoropropane-lipid microsphere |
| Octafluoropropaneor Refrigerant gas R 218 |
| Octafluoropropaneor Refrigerant gas R 218 [UN2424] [Nonflammable gas] |
| Octafluoropropaneor Refrigerant gas R 218 [UN2424] [Nonflammable gas] |
| Octafluorpropan |
| Oktafluorpropan |
| Optison |
| Optison (Salt/Mix) |
| OR022104 |
| OR242817 |
| OR338603 |
| PC6210 |
| Perfluoropropane |
| Perfluoropropane (PFC-218) 99.9% |
| Perfluoropropane 99+% |
| Perfluoropropaneminimum |
| Perflutren |
| Perflutren (Aerosomes), Bristol-Myers Squibb Medical Imaging |
| Perflutren (Aerosomes), ImaRx/DuPont |
| Perflutren (Aerosomes), Lantheus |
| Perflutren (JAN/USAN/INN) |
| Perflutren [USAN] |
| Perflutren and Human Albumin |
| Perflutren Lipid Microsphere |
| Perflutren Protein-Type A Microspheres injection |
| Perflutren-lipid microsphere |
| PFC 218 |
| Propane, 1,1,1,2,2,3,3,3-octafluoro- |
| Propane, octafluoro- |
| Propane,1,1,1,2,2,3,3,3-octafluoro- |
| QYSGYZVSCZSLHT-UHFFFAOYSA-N |
| R 218 |
| RC 218, PFC 218 |
| SBB090673 |
| UN 2424 |
| UN2424 |
| UNII-CK0N3WH0SR |
| YM-454 |
| YM454 |
| ZINC8214651 |
| ZX-AP010865 |
US Patents and Regulatory Information for DEFINITY
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lantheus Medcl | DEFINITY | perflutren | INJECTABLE;INTRAVENOUS | 021064-001 | Jul 31, 2001 | RX | Yes | Yes | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Lantheus Medcl | DEFINITY | perflutren | INJECTABLE;INTRAVENOUS | 021064-001 | Jul 31, 2001 | RX | Yes | Yes | ➤ Sign Up | ➤ Sign Up | Y | ➤ Sign Up | |||
| Lantheus Medcl | DEFINITY | perflutren | INJECTABLE;INTRAVENOUS | 021064-001 | Jul 31, 2001 | RX | Yes | Yes | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Lantheus Medcl | DEFINITY | perflutren | INJECTABLE;INTRAVENOUS | 021064-001 | Jul 31, 2001 | RX | Yes | Yes | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
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Expired US Patents for DEFINITY
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
|---|---|---|---|---|---|---|---|
| Lantheus Medcl | DEFINITY | perflutren | INJECTABLE;INTRAVENOUS | 021064-001 | Jul 31, 2001 | ➤ Sign Up | ➤ Sign Up |
| Lantheus Medcl | DEFINITY | perflutren | INJECTABLE;INTRAVENOUS | 021064-001 | Jul 31, 2001 | ➤ Sign Up | ➤ Sign Up |
| Lantheus Medcl | DEFINITY | perflutren | INJECTABLE;INTRAVENOUS | 021064-001 | Jul 31, 2001 | ➤ Sign Up | ➤ Sign Up |
| Lantheus Medcl | DEFINITY | perflutren | INJECTABLE;INTRAVENOUS | 021064-001 | Jul 31, 2001 | ➤ Sign Up | ➤ Sign Up |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
Non-Orange Book US Patents for DEFINITY
For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.
The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.
| Patent No. | Title | Estimated Patent Expiration |
|---|---|---|
| 8,084,056 | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend | ➤ Sign Up |
| 8,747,892 | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend | ➤ Sign Up |
| Patent No. | Title | Estimated Patent Expiration |
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International Patents for DEFINITY
| Country | Document Number | Estimated Expiration |
|---|---|---|
| Canada | 2317921 | ➤ Sign Up |
| Malaysia | 137255 | ➤ Sign Up |
| Slovakia | 285333 | ➤ Sign Up |
| Eurasian Patent Organization | 200000765 | ➤ Sign Up |
| Country | Document Number | Estimated Expiration |
Supplementary Protection Certificates for DEFINITY
| Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
|---|---|---|---|
| 90017-8 | Sweden | ➤ Sign Up | PRODUCT NAME: LIPIDMIKROSFAERER INNEHALLANDE PERFLUTREN; REG. NO/DATE: EU/1/06/361/001 20060920 |
| 00267 | Netherlands | ➤ Sign Up | PRODUCT NAME: PERFLUTREN BEVATTENDE LIPIDE-MICROBOLLEN; REGISTRATION NO/DATE: EU/1/06/361/001 20060920 |
| C/GB07/031 | United Kingdom | ➤ Sign Up | PRODUCT NAME: PERFLUTREN-CONTAINING LIPID MICROSPHERES; REGISTERED: UK EU/1/06/361/001 20060920 |
| Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
