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Last Updated: March 30, 2020

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ACCUPRIL Drug Profile


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Which patents cover Accupril, and when can generic versions of Accupril launch?

Accupril is a drug marketed by Pfizer Pharms and is included in one NDA.

The generic ingredient in ACCUPRIL is quinapril hydrochloride. There are eleven drug master file entries for this compound. Eleven suppliers are listed for this compound. Additional details are available on the quinapril hydrochloride profile page.

Drug patent expirations by year for ACCUPRIL
Drug Prices for ACCUPRIL

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Drug Sales Revenue Trends for ACCUPRIL

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Recent Clinical Trials for ACCUPRIL

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SponsorPhase
University of NebraskaPhase 4
Nova Scotia Health AuthorityPhase 4
Nova Scotia Health Research FoundationPhase 4

See all ACCUPRIL clinical trials

Recent Litigation for ACCUPRIL

Identify potential future generic entrants

District Court Litigation
Case NameDate
Apotex, Inc. v. Teva Pharmaceutical Industries, Ltd.2013-03-14
Apotex, Inc. v. Mylan Pharmaceuticals, Inc.2012-04-20
Apotex, Inc. v. UCB, Inc.2012-04-20

See all ACCUPRIL litigation

Synonyms for ACCUPRIL
(3S)-2-(N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid Hydrochloride
(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid;hydrochloride
(3S)-2-[(2S)-2-{[(2S)-1-ETHOXY-1-OXO-4-PHENYLBUTAN-2-YL]AMINO}PROPANOYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE
(3S)-2-{(2S)-2-[(1S)-1-ethoxycarbonyl-3-phenylpropylamino]propanoyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
(3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
(3S)-2-{N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid--hydrogen chloride (1/1)
(S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
(S)-2-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-
(S)-2-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
(S)-2-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, 1-ethyl ester, monohydrochloride
(S)-2-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid 1-Ethyl Ester Hydrochloride
[3S-[2[R*(R*)], 3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, monohydrochloride
2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
2-ylamino)propanoyl)-1,2,3,4-
3-isoquinolineacrboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, (3S-(2(R*(R*)),3R*))-
3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, monohydrochloride, (3S-(2(R*(R*)),3R*))-
3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3S-(2(R*(R*)),3R*))
3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3S-(2(R*(R*)),3R*))-
33067B3N2M
586Q558
82586-55-8
A11736
AB07655
AB2000675
AC-1655
Accupril (TN)
Accuprin
Accupro
Accupron
Accuretic
Acequin
Acuitel
Acuprel
AKOS015888532
AS-14026
Asig
C07340
C25H30N2O5.HCl
CAS-82586-55-8
CCG-39543
CHEBI:8714
CHEMBL1201011
CI 906
CI-906
CI-906 (CN-109452)
CI906
Conan
Continucor
CPD000499582
CS-2591
D00459
DSSTox_CID_1221
DSSTox_GSID_21221
DSSTox_RID_76019
DTXSID3021221
Ectren
Hemokvin
HMS1922C15
HSDB 7046
HY-B0477
IBBLRJGOOANPTQ-JKVLGAQCSA-N
Korec
Koretic
Lidaltrin
LS-85471
MCULE-2623123657
MFCD00889215
MLS001076683
NC00722
NCGC00094997-01
NCGC00167962-06
NCGC00257944-01
NE45380
NSC-758222
NSC758222
PD 109452-2
PD-109,452-2
pd-109452-2
PD-109522
Pharmakon1600-01503076
Q27108138
Quinapril hydrochloride
Quinapril (hydrochloride)
Quinapril for peak identification, European Pharmacopoeia (EP) Reference Standard
Quinapril for system suitability, European Pharmacopoeia (EP) Reference Standard
QUINAPRIL HCL
QUINAPRIL HYDROCHLORIDE
Quinapril Hydrochloride ,(S)
Quinapril hydrochloride (Accupril)
Quinapril hydrochloride (JP17/USP)
Quinapril hydrochloride [USAN:USP]
Quinapril hydrochloride [USAN]
Quinapril hydrochloride, >=98% (HPLC), solid
Quinapril hydrochloride, European Pharmacopoeia (EP) Reference Standard
Quinapril Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
Quinapril hydrochloride, United States Pharmacopeia (USP) Reference Standard
Quinapril hydrochloride;
quinapril-hydrochloride-accupril
Quinapril.HCl
Quinazil
s2581
SAM002589972
SC-17215
SCHEMBL41404
SMR000499582
SPECTRUM1503076
SR-01000765404
SR-01000765404-2
SW199393-2
tetrahydroisoquinoline-3-carboxylic
Tox21_111381
Tox21_111381_1
Tox21_200390
UNII-33067B3N2M
Paragraph IV (Patent) Challenges for ACCUPRIL
Tradename Dosage Ingredient NDA Submissiondate
ACCUPRIL TABLET;ORAL quinapril hydrochloride 019885

US Patents and Regulatory Information for ACCUPRIL

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-001 Nov 19, 1991 AB RX Yes No   Start Trial   Start Trial   Start Trial
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-004 Nov 19, 1991 AB RX Yes Yes   Start Trial   Start Trial   Start Trial
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-002 Nov 19, 1991 AB RX Yes No   Start Trial   Start Trial   Start Trial
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-003 Nov 19, 1991 AB RX Yes No   Start Trial   Start Trial   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Expired US Patents for ACCUPRIL

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-003 Nov 19, 1991   Start Trial   Start Trial
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-004 Nov 19, 1991   Start Trial   Start Trial
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-001 Nov 19, 1991   Start Trial   Start Trial
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-002 Nov 19, 1991   Start Trial   Start Trial
Pfizer Pharms ACCUPRIL quinapril hydrochloride TABLET;ORAL 019885-003 Nov 19, 1991   Start Trial   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Patent No. >Patent Expiration

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Serving leading biopharmaceutical companies globally:

McKesson
Medtronic
Baxter
Dow
Boehringer Ingelheim
Moodys

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