Last updated: April 26, 2026
Who manufactures Narcan (naloxone) in the US?
Narcan is marketed in multiple branded naloxone formats in the US. The brand owner in the US is Hikma Pharmaceuticals USA Inc. for Narcan (naloxone hydrochloride) 4 mg/actuation nasal spray under NDC 70545-0002. The label lists Janssen Biotech, Inc. as the packager for the product. This product is supplied through Hikma’s commercialization network and contract manufacturing/packaging partners used by the label.
US branded product mapping (by dosage form)
| Narcan format |
Active |
US brand holder / label holder |
Label-listed manufacturing/packaging party |
Key regulatory product anchor |
| Narcan nasal spray 4 mg/actuation |
Naloxone HCl |
Hikma Pharmaceuticals USA Inc. |
Janssen Biotech, Inc. (packager listed on label) |
NDC 70545-0002 (Narcan 4 mg/actuation nasal spray) |
Source: Narcan US prescribing information/label for the nasal spray (Hikma as label holder; Janssen Biotech as packager). [1]
Which contract manufacturing and packaging entities show up on the Narcan label?
The Narcan nasal spray label (Hikma) identifies Janssen Biotech, Inc. as the packager. Label-listed packaging does not always map 1:1 to the original drug substance or bulk drug product site, but it is the most direct, public supplier point used for commercialization and compliance.
Label-listed supplier roles (publicly shown)
| Supplier entity |
Role on Narcan label |
Product format |
Evidence |
| Janssen Biotech, Inc. |
Packager |
Narcan nasal spray 4 mg/actuation (4 mg) |
Label lists Janssen as packager for the branded nasal spray. [1] |
Source: Narcan label. [1]
What other naloxone suppliers compete in the same market category?
Narcan is a branded naloxone product. In the US, other manufacturers supply naloxone nasal spray and naloxone injectable products under different brands and generics. For supplier diligence tied to hospital and pharmacy procurement, you typically track competitors by NDC and format, because substitution rules are format-specific.
Competitive supplier categories by format
| Format |
Typical procurement suppliers |
Supplier identification method |
Why it matters |
| Naloxone nasal spray (brand and generic) |
Brand holders and generic firms |
NDC-level cataloging |
Substitution depends on device and dosing delivery |
| Naloxone injection (vials/ampules) |
Injectables manufacturers |
NDC and label manufacturing sites |
Supplies for EMS and inpatient use differ from nasal |
No additional Narcan-specific manufacturers beyond what appears on the Narcan nasal spray label can be asserted from the supplied source. The only directly evidenced Narcan “supplier” entities in the public label are the label holder and the label-listed packager. [1]
How do distributors and channels typically work for Narcan (supplier perspective)?
For business planning, “supplier” in Narcan supply-chain terms splits into three layers:
- Label holder / brand owner (commercial responsibility for the product in the market)
- Packager / contract manufacturing nodes (label-listed manufacturing/packaging)
- Wholesalers and health-system distribution (purchase and stocking routes)
The only layer that can be confirmed from the Narcan label text provided is #1 and #2 for the branded nasal spray.
Narcan supply-chain nodes evidenced from label
| Node |
Narcan nasal spray 4 mg/actuation |
Evidence |
| Label holder |
Hikma Pharmaceuticals USA Inc. |
Narcan label. [1] |
| Label-listed packager |
Janssen Biotech, Inc. |
Narcan label. [1] |
Supplier due diligence checklist tied to procurement (what to verify)
For Narcan orders, diligence should anchor to format-specific and NDC-specific sourcing:
- Confirm the NDC and dosage form you are buying (Narcan nasal spray 4 mg/actuation has a distinct NDC).
- Confirm the brand holder on the label (Hikma for Narcan nasal spray).
- Confirm the packager listed on the label (Janssen Biotech is listed as packager for the nasal spray).
- Verify that your contracting includes supply continuity for the exact device (nasal spray vs injection are not interchangeable at the procurement level).
These points reflect the label’s public, auditable supplier entries. [1]
Key Takeaways
- Narcan (naloxone) nasal spray 4 mg/actuation is labeled in the US under Hikma Pharmaceuticals USA Inc. and Janssen Biotech, Inc. is listed as the packager on the prescribing information/label. [1]
- Narcan supplier identification that is strictly supported by public labeling is limited to the label holder and label-listed packager for the branded nasal spray format. [1]
- For procurement and supply-chain risk controls, track NDC and format since naloxone products split by delivery type (nasal spray vs injection).
FAQs
1) Who is the label holder for Narcan nasal spray in the US?
Hikma Pharmaceuticals USA Inc. is the label holder for Narcan 4 mg/actuation nasal spray. [1]
2) Which company is listed as the packager for Narcan nasal spray?
Janssen Biotech, Inc. is listed as the packager on the Narcan nasal spray label. [1]
3) What is the US NDC for Narcan nasal spray 4 mg/actuation?
The Narcan nasal spray 4 mg/actuation product shown on the label is NDC 70545-0002. [1]
4) Are Narcan and naloxone injection interchangeable for sourcing?
For procurement, they are not treated as interchangeable because they are different delivery formats (nasal spray vs injection) with different NDCs and product specifications. (Format-specific substitution is practice- and policy-dependent.)
5) Can additional Narcan suppliers be named beyond the label holder and packager?
Only entities explicitly listed on the Narcan label for the referenced product format can be asserted from the available public labeling evidence, which includes the label holder and label-listed packager. [1]
References
[1] Hikma Pharmaceuticals USA Inc. Narcan (naloxone hydrochloride) 4 mg/actuation nasal spray: Prescribing information / label (US).
