Last updated: April 27, 2026
Which companies manufacture CLINIMIX 4.25/20 (sulfite free, in dextrose 20%) in plastic containers?
CLINIMIX 4.25/20 (amino acids injection with dextrose injection) is an FDA-regulated sterile parenteral nutrition (PN) product marketed under the CLINIMIX brand by Baxter Healthcare Corporation and distributed through the Baxter commercial supply chain.
Source: U.S. FDA labeling for CLINIMIX (manufacturer/distributor listed as Baxter).
Who supplies it to hospitals and wholesalers?
Distribution is handled through Baxter’s branded logistics and its contracted pharmaceutical distributors, with standard US channel coverage across national wholesalers and direct hospital purchasing contracts.
Source: Baxter product labeling and US distribution through established Baxter supply channels.
What does the “plastic container” supply model look like?
The product description “in plastic container” aligns with Baxter’s PN presentation for CLINIMIX, supplied in ready-to-use container configurations used for compounded PN workflows in hospitals.
Source: FDA labeling product presentation (plastic container format for CLINIMIX).
Supplier map (practical purchasing view)
| Supplier role |
Company |
What they supply |
Evidence |
| Manufacturer / marketing authorization holder |
Baxter Healthcare Corporation |
CLINIMIX 4.25/20 (sulfite free) PN admixture packaged in plastic containers |
FDA labeling lists Baxter as manufacturer/distributor |
| Brand distribution / order fulfillment |
Baxter commercial organization |
Direct and contracted distribution into institutional channel |
FDA labeling distribution references Baxter supply chain |
| Purchasing channels (typical) |
US pharma wholesalers and hospital group purchasing organizations |
Product via Baxter distribution networks |
Baxter distribution practice for branded sterile drugs |
SKU-level constraints that affect supplier matching
The supplier that can fill “CLINIMIX 4.25/20 SULFITE FREE IN DEXTROSE 20% IN PLASTIC CONTAINER” is constrained by:
- Exact strength: 4.25% amino acids / 20% dextrose (not 5% dextrose products, not other amino acid concentrations).
- Sulfite-free specification: affects formulation batch release and substitute selection.
- Container type: plastic container presentation limits substitutions versus bottle formats.
These constraints align with FDA labeling for the specific CLINIMIX strength and formulation attributes and therefore map back to the brand manufacturer listed in labeling (Baxter).
Key procurement implications
- If the contract product number is CLINIMIX 4.25/20 sulfite free in dextrose 20% in plastic container, the practical supplier is Baxter via its distributor network.
- Substitution risk is high if the facility uses a different CLINIMIX strength, different excipient status (sulfite content), or a different container format.
Key Takeaways
- Baxter Healthcare Corporation is the manufacturer/marketer and the core supplier source for CLINIMIX 4.25/20 sulfite free in dextrose 20% in plastic container, per FDA labeling.
- Hospital procurement and wholesaler fulfillment flow through Baxter’s distribution network rather than independent third-party manufacturing.
- Exact match is driven by strength (4.25/20), sulfite-free status, and plastic container presentation.
FAQs
1) Is CLINIMIX 4.25/20 sulfite free in dextrose 20% supplied by more than one manufacturer in the US?
The brand product is marketed with the manufacturer/distributor identified in FDA labeling as Baxter Healthcare Corporation.
2) Can wholesalers supply this CLINIMIX strength directly from Baxter?
Yes. Wholesaler orders typically route through Baxter’s distribution channels for branded sterile products.
3) What determines whether a substitute is acceptable for “sulfite free” CLINIMIX?
The sulfite-free formulation attribute tied to the specific labeled product, along with matching strength and container format.
4) Does “plastic container” affect supplier eligibility for substitutions?
Yes. The presentation is part of the labeled product format; substitutions often fail if the container type differs.
5) Where do facilities confirm the correct supplier for procurement?
Through the FDA-approved labeling for the specific CLINIMIX strength and presentation, which identifies Baxter as manufacturer/distributor.
References
[1] U.S. Food and Drug Administration. CLINIMIX (amino acids and dextrose) injection, sulfite free in dextrose 20% in plastic container: Prescribing Information/Labeling. FDA.
