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Last Updated: March 26, 2026

Suppliers and packagers for DEXTROSE 5%, SODIUM CHLORIDE 0.2% AND POTASSIUM CHLORIDE 20MEQ


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DEXTROSE 5%, SODIUM CHLORIDE 0.2% AND POTASSIUM CHLORIDE 20MEQ

Listed suppliers include manufacturers, repackagers, relabelers, and private labeling entitities.

Applicant Tradename Generic Name Dosage NDA NDA/ANDA Supplier Package Code Package Marketing Start
Baxter Hlthcare DEXTROSE 5%, SODIUM CHLORIDE 0.2% AND POTASSIUM CHLORIDE 20MEQ dextrose; potassium chloride; sodium chloride INJECTABLE;INJECTION 018037 NDA Baxter Healthcare Company 0338-0663-04 1000 mL in 1 BAG (0338-0663-04) 1979-02-02
>Applicant >Tradename >Generic Name >Dosage >NDA >NDA/ANDA >Supplier >Package Code >Package >Marketing Start

Suppliers for the Pharmaceutical Drug: DEXTROSE 5%, SODIUM CHLORIDE 0.2%, AND POTASSIUM CHLORIDE 20 MEQ

Last updated: August 4, 2025


Introduction

The pharmaceutical preparation comprising Dextrose 5%, Sodium Chloride 0.2%, and Potassium Chloride 20 mEq serves as a crucial intravenous (IV) fluid in clinical settings, primarily for hydration, electrolyte balance, and metabolic support. The procurement of high-quality excipients and ingredients is vital for ensuring safe, effective, and regulatory-compliant drug manufacturing. This article explores key suppliers capable of providing these formulations at pharmaceutical standards, focusing on their market reach, manufacturing quality, regulatory compliance, and supply stability.


Market Overview and Importance of Quality Suppliers

The global IV solution market is expansive, driven by increasing healthcare needs and advancements in medical treatments [1]. Suppliers of Dextrose, Sodium Chloride, and Potassium Chloride must adhere to strict pharmacopeial standards—United States Pharmacopeia (USP), European Pharmacopoeia (EP), or other regional standards—assuring purity, dosage accuracy, and manufacturing integrity. Quality and reliability underpin supply chain resilience, especially amid global disruptions.


Major Suppliers and Manufacturers

1. Baxter International Inc.

Overview: Baxter is a leading pharmaceutical and medical device company with extensive manufacturing capabilities for sterile solutions, including Dextrose and electrolyte supplements.

Product Range: Baxter manufactures medical-grade Dextrose 5% solutions, Sodium Chloride 0.2% solutions, and Potassium Chloride 20 mEq solutions, compliant with USP and EP standards.

Quality & Compliance: Known for rigorous quality assurance, Baxter’s products are validated for sterility, stability, and consistency, approved by major regulatory authorities such as FDA, EMA, and Health Canada.

Supply Capabilities: Baxter's global footprint ensures robust supply chains, serving hospitals and pharmaceutical companies worldwide with reliable delivery schedules.

2. B. Braun Melsungen AG

Overview: B. Braun specializes in manufacturing sterile infusion solutions, with extensive experience in electrolyte preparations.

Product Range: Offers Dextrose solutions at various concentrations, along with electrolyte additives including Sodium Chloride and Potassium Chloride, conforming to pharmacopeial standards.

Quality & Compliance: B. Braun emphasizes Good Manufacturing Practice (GMP), with products validated for purity, endotoxin levels, and stability.

Supply Capabilities: They possess manufacturing sites across Europe, Asia, and North America, ensuring continuity of supply aligned with global health demands.

3. Fresenius Kabi

Overview: Fresenius Kabi is renowned for producing sterile infusion solutions for parenteral nutrition and reconstitution.

Product Range: Provides Dextrose 5%, Sodium Chloride 0.2%, and Potassium Chloride 20 mEq, available in various container types suited for clinical use.

Quality & Compliance: Their manufacturing adheres to stringent ISO standards, and products are compliant with pharmacopeias, with continuous quality testing.

Supply Capabilities: With manufacturing facilities globally, Fresenius ensures scalable and timely supply, including customized formulations where necessary.

4. Hikma Pharmaceuticals

Overview: Hikma is a key player in sterile injectables and IV solutions, serving markets across Europe, the Middle East, and North America.

Product Range: Offers Dextrose solutions and electrolytes, including Potassium Chloride, meeting pharmacopeial requirements.

Quality & Compliance: Recognized for high-quality standards, GMP adherence, and strong regulatory track record.

Supply Capabilities: Known for reliable supply channels and responsive customer service, capable of meeting large-volume demands.

5. Pfizer Inc.

Overview: Pfizer manufactures a variety of intravenous solutions, including basic electrolyte and dextrose formulations.

Product Range: Provides ready-to-use IV fluids, with ingredients sourced from approved suppliers meeting pharmacopeial standards.

Quality & Compliance: Pfizer’s products undergo rigorous validation, with an emphasis on stability, sterility, and safety.

Supply Capabilities: As a major global pharmaceutical company, Pfizer has extensive logistics networks to ensure uninterrupted supply.


Key Criteria for Supplier Selection

  • Regulatory Compliance: Suppliers must hold certifications such as FDA approval, EMA authorization, and ISO certifications.
  • Quality Assurance: High standards in sterility, endotoxin elimination, and assay accuracy.
  • Manufacturing Capacity: Ability to meet large and just-in-time demands, particularly during global crises.
  • Supply Chain Stability: Resilient logistics, contingency plans, and geographic diversification.
  • Pricing and Contract Flexibility: Competitive pricing models combined with flexible procurement terms.

Emerging Suppliers and Alternatives

Several emerging manufacturers in Asia and Eastern Europe are expanding capacity for pharmaceutical-grade excipients, including Sun Pharmaceutical Industries, Hunan Sinoscience Pharmaceutical, and Guangzhou Pharma. While these suppliers offer cost advantages, rigorous vetting for compliance and quality assurance is essential before integration into supply chains.


Regulatory and Quality Considerations

Pharmaceutical-grade ingredients must conform to pharmacopeial standards, including heavy metal limits, endotoxin levels, and microbial limits. Suppliers must demonstrate certification compliance, GMP adherence, and provide Certificates of Analysis (CoA) for each batch, ensuring batch-to-batch consistency critical in IV solutions.


Supply Chain and Logistics

Given the criticality of these components in clinical and hospital settings, suppliers should demonstrate supply chain robustness, including diversified sourcing, inventory management, and contingency strategies for disruptions. Regular communication and forecasting collaboration are vital for maintaining stable supplies.


Conclusion

Procurement of Dextrose 5%, Sodium Chloride 0.2%, and Potassium Chloride 20 mEq for pharmaceutical manufacturing hinges on selecting suppliers committed to high-quality standards, regulatory compliance, and supply reliability. Major players like Baxter, B. Braun, Fresenius Kabi, Hikma, and Pfizer stand out as dependable sources globally. Collaborating with these suppliers ensures pharmaceutical integrity, safety, and consistency in patient care.


Key Takeaways

  • Ensuring supplier adherence to pharmacopeial standards is non-negotiable for IV solution ingredients.
  • Major pharmaceutical manufacturers possess the capacity, quality assurance, and regulatory approvals necessary for reliable supply.
  • Emerging suppliers require thorough vetting to meet pharmaceutical standards before integration.
  • Supply chain stability and logistics efficiency are critical amidst global disruptions, making diversified sourcing advantageous.
  • Regular audits, certifications, and Certificates of Analysis are essential components of supplier qualification.

FAQs

Q1: What are the primary regulatory standards for suppliers of pharmaceutical excipients like Dextrose and electrolytes?
A1: The primary standards include the United States Pharmacopeia (USP), European Pharmacopoeia (EP), and Japanese Pharmacopoeia, which specify purity, contamination limits, and packaging requirements.

Q2: How can I verify supplier compliance and quality assurance?
A2: Verify certifications such as FDA approval, ISO 9001/13485, and GMP compliance through audits, supplier audits, and reviewing Certificates of Analysis (CoA) for each batch.

Q3: Are there cost-effective alternative suppliers for these ingredients?
A3: Yes, emerging suppliers, particularly from Asia, may offer competitive pricing but require rigorous qualification to ensure they meet pharmacopeial standards and quality requirements.

Q4: What are the main challenges in sourcing these ingredients globally?
A4: Challenges include regulatory variations, geopolitical issues affecting trade, raw material shortages, and disruptions due to pandemics or natural disasters.

Q5: How important is supply chain diversification for sourcing these ingredients?
A5: Highly important; diversification reduces dependence on single-source suppliers, buffers against disruptions, and ensures continuous availability for critical medications.


References

  1. MarketsandMarkets. Intravenous Solutions Market by Type, Application, and Region — Global Forecast to 2027.

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