Last updated: April 28, 2026
Which companies supply bupivacaine liposome products used in clinical or commercial settings?
Bupivacaine liposome is a formulation category that appears in branded products and, separately, as components used by developers. The supplier landscape splits into two buckets:
1) Branded, market-facing manufacturers (product suppliers)
2) Upstream suppliers of enabling inputs (lipid components, manufacturing services, and contract development and manufacturing organizations)
This response covers product suppliers only where the supplier identity is clearly tied to a specific bupivacaine liposome product name.
Product supplier map (branded bupivacaine liposome)
| Bupivacaine liposome product (common reference) |
Supplier / manufacturer |
Role in supply chain |
| EXPAREL (bupivacaine liposome injectable suspension) |
Pacira BioSciences, Inc. |
Product manufacturer / marketing authorization holder in the US |
Source: Pacira product information for EXPAREL (bupivacaine liposome injectable suspension). [1]
Are there multiple “bupivacaine liposome” suppliers beyond EXPAREL?
A second supplier identity depends on whether the request targets:
- Exact branded products (where the supplier is a legal entity tied to that product), or
- Unbranded “bupivacaine liposome” APIs or excipient systems (where suppliers differ by lipid composition and contract manufacturing arrangement).
No additional branded “bupivacaine liposome” supplier names are provided in the available basis used here beyond the EXPAREL manufacturer above. [1]
What counts as “supplier” for bupivacaine liposome procurement?
In procurement and due diligence, “supplier” usually means one of these:
- Finished dosage form supplier (injectable suspension in labeled packaging)
- Marketing authorization holder / product manufacturer (entity responsible for commercial release)
- Contract development and manufacturing organization (CDMO) (entity producing under contract)
- Material suppliers (key lipids, buffers, and fill-finish consumables)
For decision-making tied to patient access or contracting, the most direct supplier in this formulation category is the finished product manufacturer for the named branded product.
What is the single most direct product supplier for bupivacaine liposome procurement in the US?
Pacira BioSciences, Inc.
| Company |
Product |
Procurement implication |
| Pacira BioSciences, Inc. |
EXPAREL (bupivacaine liposome injectable suspension) |
Direct commercial product supply for the branded bupivacaine liposome product |
Source: EXPAREL prescribing information lists Pacira BioSciences, Inc. as the manufacturer. [1]
What suppliers provide the core bupivacaine liposome system (lipids, manufacturing inputs)?
The supplier set for lipid components and contract manufacturing services is formulation-specific and depends on the exact liposome composition and manufacturing process used by a given product. The supplier list is not determinable from the cited basis used here because no supplier names for lipid ingredients or CDMO/manufacturing inputs are provided in the available references.
How to structure supplier outreach for bupivacaine liposome in practice
Use a two-track procurement plan:
- Track 1: Finished product (contract with product manufacturer or authorized distributor)
- Target: Pacira BioSciences, Inc. for EXPAREL in the US context. [1]
- Track 2: Development-grade supply (for investigational or generic/formulation work)
- Target: CDMOs and lipid suppliers chosen based on the exact formulation and process requirements.
Only Track 1 is explicitly supported by supplier identity in the available source basis.
Key Takeaways
- Pacira BioSciences, Inc. is the identified product supplier/manufacturer for EXPAREL (bupivacaine liposome injectable suspension). [1]
- Additional “bupivacaine liposome” suppliers can exist for investigational formulations or non-branded ingredient systems, but they are not named in the cited basis used here.
FAQs
1) Who manufactures EXPAREL (bupivacaine liposome)?
Pacira BioSciences, Inc. [1]
2) Is Pacira the supplier for all bupivacaine liposome products?
The identified supplier in the cited basis is tied to EXPAREL. [1]
3) Do bupivacaine liposome suppliers include CDMOs?
Yes in principle, but specific CDMO supplier names are not provided in the cited basis used here.
4) What is the most direct supplier route for bupivacaine liposome in the US?
Contract with the EXPAREL product manufacturer or its authorized channels, where the manufacturer is Pacira BioSciences, Inc. [1]
5) What supplier category matters most for contracting at hospitals or IDNs?
The finished product supplier for the labeled injectable suspension (for EXPAREL, Pacira). [1]
References
[1] Pacira BioSciences, Inc. EXPAREL (bupivacaine liposome injectable suspension) Prescribing Information.
