Last Updated: November 9, 2026

Details for Patent: RE46792

Name: Drug Patent Intelligence for US Patent RE46792
Creator: DrugPatentWatch
License: https://www.drugpatentwatch.com/terms.php

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Which drugs does patent RE46792 protect, and when does it expire?

Patent RE46792 protects ADQUEY and is included in one NDA.

This patent has twenty-nine patent family members in twenty-two countries.

Summary for Patent: RE46792

Title:	Oxazole compound and pharmaceutical composition
Abstract:	The present invention provides a oxazole compound represented by Formula (1), or a salt thereof: wherein R1 is an aryl group which may have one or more substituents; R2 is an aryl group or a nitrogen atom-containing heterocyclic group each of which may have one or more substituents; and W is a divalent group represented by —Y1-A1- or or —Y2—C(═O)— wherein Y1 is a group such as —C(═O)—, A1 is a group such as a lower alkylene group, and Y2 is a group such as a piperazinediyl group. The oxazole compound has a specific inhibitory action against phosphodiesterase 4.
Inventor(s):	Minoru Okada, Masaya Kato, Norifumi Sato, Tetsuyuki Uno, Hideki Kitagaki, Junpei Haruta, Hidetaka Hiyama, Tomonori Shibata
Assignee:	Otsuka Pharmaceutical Co Ltd
Application Number:	US15/623,249
Patent Claim Types: see list of patent claims	Use; Composition;

Drugs Protected by US Patent RE46792

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Acrotech Biopharma	ADQUEY	difamilast	OINTMENT;TOPICAL	219474-001	Feb 12, 2026		RX	Yes	Yes	⤷ Start Trial	⤷ Start Trial	Y	Y		METHOD OF TREATING ATOPIC DERMATITIS	⤷ Start Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent RE46792

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Argentina	057891	⤷ Start Trial
Argentina	109006	⤷ Start Trial
Argentina	109007	⤷ Start Trial
Australia	2006316079	⤷ Start Trial
Brazil	PI0618589	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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