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Details for Patent: 9,453,006

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Patent 9,453,006 protects LUZU and is included in one NDA.

This patent has six patent family members in five countries.

Summary for Patent: 9,453,006

Title:Crystalline form having specific crystal habit and pharmaceutical composition containing this crystalline form as active ingredient
Abstract: Means for improving the solubility of luliconazole is provided. A crystal of luliconazole represented by the following formula is provided, wherein the crystal has such a crystal habit that (011) plane is a specific crystal growth plane. The crystal is characterized in that I.sub.(011) with respect to a sum total of I.sub.(001), I.sub.(100), I.sub.(10-1), I.sub.(011), I.sub.(110), I.sub.(11-1), I.sub.(10-2), I.sub.(11-2), I.sub.(020), I.sub.(021), I.sub.(20-2), I.sub.(121), I.sub.(013), I.sub.(11-3), and I.sub.(221) is not less than 25%, provided that integrated intensities of diffraction peaks, which correspond to the (001), (100), (10-1), (011), (110), (11-1), (10-2), (11-2), (020), (021), (20-2), (121), (013), (11-3), and (221) planes, are designated as I.sub.(001), I.sub.(100), I.sub.(10-1), I.sub.(011), I.sub.(110), I.sub.(11-1), I.sub.(10-2), I.sub.(11-2), I.sub.(020), I.sub.(021), I.sub.(20-2), I.sub.(121), I.sub.(013), I.sub.(11-3), and I.sub.(221) respectively in relation to the diffraction peaks detected in a range of 2.theta.=5 to 35.degree. in a powder X-ray diffractometry using CuK.alpha. radiation. ##STR00001##
Inventor(s): Masuda; Takaaki (Kanagawa, JP), Miyata; Yoshiyuki (Tokyo, JP), Kaneda; Hideo (Tokyo, JP)
Assignee: POLA PHARMA INC. (Tokyo, JP) NIHON NOHYAKU CO., LTD. (Tokyo, JP)
Application Number:14/388,218
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Medicis
LUZU
luliconazole
CREAM;TOPICAL204153-001Nov 14, 2013RXYes9,453,006► subscribeY
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International Patent Family for Patent: 9,453,006

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
China105026390► subscribe
European Patent Office2964641► subscribe
Japan5589110► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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