Last Updated: November 12, 2026

Details for Patent: 9,446,059

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Which drugs does patent 9,446,059 protect, and when does it expire?

Patent 9,446,059 protects VYALEV and is included in one NDA.

This patent has seventy-two patent family members in thirty-seven countries.

Summary for Patent: 9,446,059
Title:Carbidopa and L-dopa prodrugs and methods of use
Abstract:The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
Inventor(s):Benoit CARDINAL-DAVID, Vincent S. Chan, Kassibla E. DEMPAH, Brian P. ENRIGHT, Rodger F. Henry, Raimundo HO, Ye Huang, Alexander D. HUTERS, Russell C. Klix, Scott W. KRABBE, Philip R. Kym, Yanbin Lao, Xiaochun Lou, Sean E. Mackey, Mark A. Matulenko, Peter T. Mayer, Christopher P. Miller, James Stambuli, Eric A. Voight, Zhi Wang, Geoff G. Zhang, Valentino J. Stella
Assignee: AbbVie Inc
Application Number:US14/919,418
Patent Claim Types:
see list of patent claims
Use; Device;

Drugs Protected by US Patent 9,446,059

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Abbvie VYALEV foscarbidopa; foslevodopa SOLUTION;SUBCUTANEOUS 216962-001 Oct 16, 2024 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y Y TREATMENT OF MOTOR FLUCTUATIONS IN ADULTS WITH ADVANCED PARKINSON'S DISEASE ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 9,446,059

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 3209302 ⤷  Start Trial 2023C/510 Belgium ⤷  Start Trial
European Patent Office 3209302 ⤷  Start Trial 301224 Netherlands ⤷  Start Trial
European Patent Office 3209302 ⤷  Start Trial CA 2023 00015 Denmark ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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