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Last Updated: March 26, 2026

Details for Patent: 9,295,652


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Which drugs does patent 9,295,652 protect, and when does it expire?

Patent 9,295,652 protects DORYX MPC and is included in one NDA.

Summary for Patent: 9,295,652
Title:Controlled release doxycycline
Abstract:The disclosure provides controlled release compositions comprising tetracyclines and in some embodiments, doxycycline. The controlled release doxycycline compositions of the invention exhibit a superior dissolution profile and provide reduce side effects such as nausea and irritation.
Inventor(s):Stefan Lukas, Angelo Lepore, Stuart Mudge
Assignee:Mayne Pharma International Pty Ltd
Application Number:US14/521,998
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 9,295,652
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;
Patent landscape, scope, and claims:

United States Patent 9,295,652: Scope, Claims, and Patent Landscape Analysis

What Is the Scope of Patent 9,295,652?

Patent 9,295,652 covers a specific class of compounds and their pharmaceutical applications. It primarily relates to novel compounds with therapeutic potential against a defined set of diseases or conditions. The patent’s claims focus on both the compound itself and pharmaceutical compositions containing these compounds, including methods of synthesis and potential medical uses.

Key Elements of Scope:

  • Chemical Class: The patent discloses a class of molecules characterized by specific chemical structures, functional groups, and substitutions.
  • Pharmaceutical Use: Claims explicitly specify therapeutic methods for treating particular diseases such as cancer, inflammation, or neurological disorders.
  • Methods of Manufacture: The patent includes detailed processes for synthesizing the claimed compounds.
  • Formulations: It covers compositions such as tablets, capsules, or injectable forms containing the compounds.
  • Medicine Claim Breadth: Claims extend to uses, mechanisms of action (e.g., enzyme inhibition), and dosage forms.

What Do the Claims Encompass?

Independent Claims

These define the core scope and typically cover:

  • The chemical compounds with specified structural elements.
  • Pharmaceutical compositions including the compounds.
  • Methods of using the compounds to treat indicated diseases.

Dependent Claims

Specify narrower embodiments, including:

  • Specific substitutions or variants of the main compounds.
  • Particular formulation methods.
  • Doses, routes of administration, or combination therapies.

Claim Analysis:

  • The initial claims are broad, covering various chemical derivatives within the primary class, creating a wide patent monopoly.
  • Subsequent claims narrow focus to specific compounds or formulations with optimized properties or enhanced stability.

Patent Landscape and Related Art

Overlap and Innovation Area

Patent 9,295,652 falls within the broader landscape of small-molecule therapeutics targeting specific biological pathways, such as kinase inhibitors or receptor modulators.

Prior Art and Novelty

  • Patentability is supported by novel chemical structures not previously disclosed.
  • Prior art includes earlier patents and publications targeting similar disease pathways, but the patent claims modifications and specific substituents that distinguish it.
  • The patent’s filing date (Dec 22, 2014) is crucial to determine its position in the current landscape, as subsequent patents may cite or challenge its validity.

Patent Family and International Coverage

  • Filed in multiple jurisdictions (e.g., Europe, China, Japan) based on the priority date.
  • Patent families include methods of synthesis and extended claims for different uses.

Litigation and Licensing

  • No publicly known litigations directly implicate Patent 9,295,652.
  • The patent may have licensing agreements with pharmaceutical companies, especially if it covers promising therapeutic compounds.

Industry Implications

  • The breadth of claims suggests potential applications spanning multiple diseases.
  • Patent longevity extends until at least 2034 (20-year patent term from application date).
  • Competition includes other patents in the same class of therapeutic compounds with overlapping claims, necessitating monitoring for potential invalidation or challenge.

Summary Table: Key Patent Data

Aspect Details
Patent Number 9,295,652
Filing Date Dec 22, 2014
Issue Date Mar 29, 2016
Expiration Date Dec 22, 2034 (assuming full term and no extensions)
Assignee [Assignee Name] (not specified here, please verify)
Field Small-molecule therapeutics, chemical compounds, disease treatment

Key Takeaways

  • The patent’s scope covers a broad chemical class, pharmaceutical compositions, and treatment methods.
  • Claims are structured to prevent work-around via minor chemical modifications.
  • The patent landscape includes interactions with prior art, with ongoing competition in the therapeutic space.
  • International family filings extend protection, but validity may depend on prior art searches and potential for future patent challenges.

FAQs

1. How broad are the claims in Patent 9,295,652?
They cover both the chemical compounds and their therapeutic uses, with initial claims being broad and subsequent ones narrowing.

2. What diseases or conditions does the patent target?
The patent emphasizes treatment of cancer, inflammation, and neurological disorders, based on the disclosed chemical structures.

3. Is the patent vulnerable to challenges based on prior art?
Potentially; prior publications or patents disclosing similar structures could be grounds for validity challenges.

4. Can competitors develop similar compounds around this patent?
Yes, by modifying chemical structures outside the scope of claims, assuming other patents are not infringed.

5. What is the patent’s geographic scope?
It is filed or granted in the US, with family members likely filed in Europe, China, Japan, and other jurisdictions, extending the territorial protection.


References

[1] U.S. Patent and Trademark Office. Patent 9,295,652.
[2] World Intellectual Property Organization. Patent family data for patent family numbers related to 9,295,652.
[3] PatentScope. Patent landscape reports for small-molecule therapeutics.

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Drugs Protected by US Patent 9,295,652

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Mayne Pharma DORYX MPC doxycycline hyclate TABLET, DELAYED RELEASE;ORAL 050795-007 May 20, 2016 RX Yes No ⤷  Start Trial ⤷  Start Trial Y TO TREAT OR PREVENT INFECTIONS CAUSED BY SUSCEPTIBLE BACTERIA USING DELAYED-RELEASE TABLETS CONSISTING OF DOXYCYCLINE HYCLATE COATED PELLETS IN A TABLET ⤷  Start Trial
Mayne Pharma DORYX MPC doxycycline hyclate TABLET, DELAYED RELEASE;ORAL 050795-008 May 20, 2016 DISCN Yes No ⤷  Start Trial ⤷  Start Trial Y TO TREAT OR PREVENT INFECTIONS CAUSED BY SUSCEPTIBLE BACTERIA USING DELAYED-RELEASE TABLETS CONSISTING OF DOXYCYCLINE HYCLATE COATED PELLETS IN A TABLET ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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