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Last Updated: December 7, 2022

Details for Patent: 8,685,980

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Summary for Patent: 8,685,980
Title:Pyrrolopyrimidine compounds and their uses
Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein. ##STR00001##
Inventor(s): Besong; Gilbert Ebai (Bad Duerkheim, DE), Brain; Christopher Thomas (North Reading, MA), Brooks; Clinton Alan (Smyrna, GA), Congreve; Miles Stuart (Royston, GB), Dagostin; Claudio (Cambridge, GB), He; Guo (Lexington, MA), Hou; Ying (Belmont, MA), Howard; Steven (Cambridge, GB), Li; Yue (Shanghai, CN), Lu; Yipin (Dublin, CA), Mortenson; Paul Neil (Cambridge, GB), Smith; Troy D. (Nashua, NH), Sung; Moo Je (Belmont, MA), Woodhead; Steven John (San Diego, CA), Wrona; Wojciech (Waltham, MA), Lagu; Bharat (Acton, MA)
Assignee: Novartis AG (Basel, CH) Astex Therapeutics, Ltd. (Cambridge, GB)
Application Number:13/060,154
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,685,980
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 8,685,980

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Novartis KISQALI ribociclib succinate TABLET;ORAL 209092-001 Mar 13, 2017 RX Yes Yes See Plans and Pricing See Plans and Pricing Y Y See Plans and Pricing
Novartis KISQALI FEMARA CO-PACK (COPACKAGED) letrozole; ribociclib succinate TABLET;ORAL 209935-001 May 4, 2017 RX Yes Yes See Plans and Pricing See Plans and Pricing Y Y See Plans and Pricing
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,685,980

PCT Information
PCT FiledAugust 20, 2009PCT Application Number:PCT/EP2009/060793
PCT Publication Date:February 25, 2010PCT Publication Number: WO2010/020675

International Family Members for US Patent 8,685,980

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 073116 See Plans and Pricing
Argentina 111763 See Plans and Pricing
Australia 2009284098 See Plans and Pricing
Brazil PI0917791 See Plans and Pricing
Canada 2734802 See Plans and Pricing
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Johnson and Johnson

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