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Last Updated: December 3, 2022

Details for Patent: 8,680,124


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Which drugs does patent 8,680,124 protect, and when does it expire?

Patent 8,680,124 protects STIVARGA and is included in one NDA.

This patent has six patent family members in five countries.

Summary for Patent: 8,680,124
Title:Treatment of cancers with acquired resistance to kit inhibitors
Abstract: The present invention provides compositions and uses thereof for treating cancers which have acquired resistance to a KIT inhibitor by administering effective amounts of DAST (4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyrid- ine-2-carboxylic acid methylamide).
Inventor(s): Wilhelm; Scott (Morristown, NJ), Gedrich; Richard W. (Louisville, CO)
Assignee: Bayer Healthcare LLC (Whippany, NJ)
Application Number:12/523,652
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,680,124
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 8,680,124

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bayer Hlthcare STIVARGA regorafenib TABLET;ORAL 203085-001 Sep 27, 2012 RX Yes Yes See Plans and Pricing See Plans and Pricing TREATMENT OF PATIENTS WITH GASTROINTESTINAL STROMAL TUMOR (GIST), INCLUDING BUT NOT LIMITED TO PATIENTS PREVIOUSLY TREATED WITH IMATINIB AND PATIENTS WITH GIST HAVING RESISTANCE TO A KIT TYROSINE KINASE INHIBITOR See Plans and Pricing
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,680,124

PCT Information
PCT FiledJanuary 18, 2008PCT Application Number:PCT/US2008/051406
PCT Publication Date:July 24, 2008PCT Publication Number: WO2008/089389

International Family Members for US Patent 8,680,124

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada 2675980 See Plans and Pricing
European Patent Office 2129376 See Plans and Pricing
Spain 2429107 See Plans and Pricing
Japan 2010516693 See Plans and Pricing
Japan 5885012 See Plans and Pricing
World Intellectual Property Organization (WIPO) 2008089389 See Plans and Pricing
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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