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Details for Patent: 8,680,124

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Patent 8,680,124 protects STIVARGA and is included in one NDA. There has been one Paragraph IV challenge on Stivarga.

This patent has six patent family members in five countries.

Summary for Patent: 8,680,124

Title:Treatment of cancers with acquired resistance to kit inhibitors
Abstract: The present invention provides compositions and uses thereof for treating cancers which have acquired resistance to a KIT inhibitor by administering effective amounts of DAST (4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyrid- ine-2-carboxylic acid methylamide).
Inventor(s): Wilhelm; Scott (Morristown, NJ), Gedrich; Richard W. (Louisville, CO)
Assignee: Bayer Healthcare LLC (Whippany, NJ)
Application Number:12/523,652
Patent Claim Types:
see list of patent claims
Use;
Patent Metrics:
Source: PatentQuant.com
Field: Pharmaceuticals
Back Citations: 0th percentile
Forward Citations: 0th percentile

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Bayer Hlthcare
STIVARGA
regorafenib
TABLET;ORAL203085-001Sep 27, 2012RXYes8,680,124► subscribe TREATMENT OF PATIENTS WITH GASTROINTESTINAL STROMAL TUMOR (GIST), INCLUDING BUT NOT LIMITED TO PATIENTS PREVIOUSLY TREATED WITH IMATINIB AND PATIENTS WITH GIST HAVING RESISTANCE TO A KIT TYROSINE KINASE INHIBITOR
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Foreign Priority and PCT Information for Patent: 8,680,124

PCT Information
PCT FiledJanuary 18, 2008PCT Application Number:PCT/US2008/051406
PCT Publication Date:July 24, 2008PCT Publication Number: WO2008/089389

International Patent Family for Patent: 8,680,124

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Japan2010516693► subscribe
Japan5885012► subscribe
Canada2675980► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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