Details for Patent: 8,455,494
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Which drugs does patent 8,455,494 protect, and when does it expire?
Patent 8,455,494 protects YUVEZZI and is included in one NDA.
This patent has one patent family member in one country.
Summary for Patent: 8,455,494
| Title: | Preparations and methods for ameliorating or reducing presbyopia |
| Abstract: | This application relates to the use of one or more parasympathomimetic drugs in combination with one or more alpha agonists to create optically beneficial miosis to, for example, temporarily treat presbyopia. The invention provides a pharmaceutical preparation comprising a therapeutically effective amount of one or more parasympathomimetic drugs or cholinesterase inhibitors, or a pharmaceutically acceptable salt thereof, in combination with one or more alpha agonists or antagonists, or a pharmaceutically acceptable salt thereof. The invention further provides for a method for treating, ameliorating or reducing presbyopia of a patient having an eye, comprising administering to said eye a pharmaceutically effective amount of the ophthalmic preparation. |
| Inventor(s): | Herbert E. Kaufman |
| Assignee: | Visus Therapeutics Inc |
| Application Number: | US13/605,302 |
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Patent Claim Types: see list of patent claims | Use; |
Drugs Protected by US Patent 8,455,494
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Visus | YUVEZZI | brimonidine tartrate; carbachol | SOLUTION/DROPS;OPHTHALMIC | 220142-001 | Jan 28, 2026 | RX | Yes | Yes | ⤷ Start Trial | ⤷ Start Trial | TREATMENT OF PRESBYOPIA | ⤷ Start Trial | ||||
| Visus | YUVEZZI | brimonidine tartrate; carbachol | SOLUTION/DROPS;OPHTHALMIC | 220142-001 | Jan 28, 2026 | RX | Yes | Yes | ⤷ Start Trial | ⤷ Start Trial | USE OF YUVEZZI FOR THE TREATMENT OF PRESBYOPIA IN ADULTS | ⤷ Start Trial | ||||
| Visus | YUVEZZI | brimonidine tartrate; carbachol | SOLUTION/DROPS;OPHTHALMIC | 220142-001 | Jan 28, 2026 | RX | Yes | Yes | ⤷ Start Trial | ⤷ Start Trial | TREATMENT OF PRESBYOPIA IN ADULTS BY ADMINISTRATION OF BRIMONIDINE AND CARBACHOL ONCE DAILY | ⤷ Start Trial | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,455,494
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| World Intellectual Property Organization (WIPO) | 2010135731 | ⤷ Start Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
