Last Updated: October 26, 2026

Details for Patent: 8,445,515


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Which drugs does patent 8,445,515 protect, and when does it expire?

Patent 8,445,515 protects TAVNEOS and is included in one NDA.

This patent has sixty-nine patent family members in thirty-six countries.

Summary for Patent: 8,445,515
Title:C5aR antagonists
Abstract:Compounds are provided that are modulators of the C5a receptor. The compounds are substituted piperidines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of C5a receptors.
Inventor(s):Pingchen Fan, Kevin Lloyd Greenman, Manmohan Reddy Leleti, Yandong Li, Jay Powers, Hiroko Tanaka, Ju Yang, Yibin Zeng
Assignee: Chemocentryx Inc
Application Number:US12/643,229
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,445,515
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 8,445,515

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Chemocentryx TAVNEOS avacopan CAPSULE;ORAL 214487-001 Oct 7, 2021 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,445,515

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 2381778 ⤷  Start Trial 301166 Netherlands ⤷  Start Trial
European Patent Office 3508477 ⤷  Start Trial PA2022006 Lithuania ⤷  Start Trial
European Patent Office 2381778 ⤷  Start Trial 2022C/518 Belgium ⤷  Start Trial
European Patent Office 2381778 ⤷  Start Trial LUC00258 Luxembourg ⤷  Start Trial
European Patent Office 2381778 ⤷  Start Trial CA 2022 00022 Denmark ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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