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Serving leading biopharmaceutical companies globally:

Harvard Business School
Accenture
Cerilliant
Moodys
Federal Trade Commission
Covington
Fuji
US Army
Queensland Health
Argus Health

Generated: February 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,227,230

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Which drugs does patent 8,227,230 protect, and when does it expire?

Patent 8,227,230 protects ELELYSO and is included in one NDA.

This patent has seventy-four patent family members in twenty-five countries.
Summary for Patent: 8,227,230
Title:Human lysosomal proteins from plant cell culture
Abstract: A device, system and method for producing glycosylated proteins in plant culture, particularly proteins having a high mannose glycosylation, while targeting such proteins with an ER signal and/or by-passing the Golgi. The invention further relates to vectors and methods for expression and production of enzymatically active high mannose lysosomal enzymes using transgenic plant root, particularly carrot cells. More particularly, the invention relates to host cells, particularly transgenic suspended carrot cells, vectors and methods for high yield expression and production of biologically active high mannose Glucocerebrosidase (GCD). The invention further provides for compositions and methods for the treatment of lysosomal storage diseases.
Inventor(s): Shaaltiel; Yoseph (Kibbutz HaSolelim-Doar-Na HaMovil, IL), Baum; Gideon (Kibbutz Ayelet HaShachar-D.N. Upper Galilee, IL), Bartfeld; Daniel (Moran--Doar-Na Bikat Beit HaKerem, IL), Hashmueli; Sharon (Ramot-Naftali, IL), Lewkowicz; Ayala (Kfar-Vradim, IL)
Assignee: Protalix Ltd. (Carmiel, IL)
Application Number:13/080,692
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 8,227,230

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Pfizer ELELYSO taliglucerase alfa POWDER;IV (INFUSION) 022458-001 May 1, 2012 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y Y ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 8,227,230

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Israel155588Apr 27, 2003

Non-Orange Book US Patents Family Members for Patent 8,227,230

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,391,638 Cell/tissue culturing device and method ➤ Try a Free Trial
8,741,620 Human lysosomal proteins from plant cell culture ➤ Try a Free Trial
8,790,641 Production of high mannose proteins in plant culture and therapeutic uses thereof ➤ Try a Free Trial
9,220,737 Plant cell culture expressing human lysosomal proteins and uses thereof ➤ Try a Free Trial
7,951,557 Human lysosomal proteins from plant cell culture ➤ Try a Free Trial
8,449,876 Human lysosomal proteins from plant cell culture ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 8,227,230

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Ukraine 89944 ➤ Try a Free Trial
Slovenia 2333083 ➤ Try a Free Trial
Singapore 2013021217 ➤ Try a Free Trial
Singapore 2007172737 ➤ Try a Free Trial
Russian Federation 2009143751 ➤ Try a Free Trial
Russian Federation 2535342 ➤ Try a Free Trial
Russian Federation 2009148012 ➤ Try a Free Trial
Russian Federation 2385928 ➤ Try a Free Trial
Russian Federation 2005136874 ➤ Try a Free Trial
Portugal 2333083 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Cerilliant
Julphar
Chinese Patent Office
Baxter
Express Scripts
AstraZeneca
Moodys
Colorcon
McKesson

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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