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|Title:||Solid pharmaceutical dosage form|
|Abstract:||A solid pharmaceutical dosage form providing improved oral bioavailability is disclosed for inhibitors of HIV protease. In particular, the dosage form comprises a solid dispersion of at least one HIV protease inhibitor and at least one pharmaceutically acceptable water-soluble polymer and at least one pharmaceutically acceptable surfactant, said pharmaceutically acceptable water-soluble polymer having a Tg of at least about 50.degree. C. Preferably, the pharmaceutically acceptable surfactant has an HLB value of from about 4 to about 10.|
|Inventor(s):||Berndl; Gunther (Herxheim, DE), Rosenberg; Joerg (Ellerstadt, DE), Liepold; Bernd (Dossenheim, DE), Breitenbach; Joerg (Mannheim, DE), Reinhold; Ulrich (Heidelberg, DE), Alani; Laman (Foster City, CA), Ghosh; Soumojeet (Lansdale, PA)|
|Assignee:||Abbott Laboratories (Abbott Park, IL)|
Patent Claim Types:|
see list of patent claims
|Dosage form; Formulation;|
Field: Organic fine chemistry
Back Citations: 196th percentile
Forward Citations: 5th percentile
|Applicant||Tradename||Generic Name||Dosage||NDA||Approval Date||Type||RLD||Patent No.||Patent Expiration||Product||Substance||Delist Req.||Patented / Exclusive Use|
|TABLET;ORAL||021906-002||Nov 9, 2007||RX||No||8,025,899*PED||► subscribe||Y|
|TABLET;ORAL||021906-001||Oct 28, 2005||RX||Yes||8,025,899*PED||► subscribe||Y|
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