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Serving hundreds of leading biopharmaceutical companies globally:

US Army
McKinsey
Chinese Patent Office
Citi
Merck
Baxter
Johnson and Johnson
UBS
Argus Health

Generated: May 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 7,767,429

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Summary for Patent: 7,767,429
Title:Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
Abstract:The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGP's), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally active polypeptide domains of the soluble, neutral active sHASEGP domains are described that include asparagine-linked sugar moieties required for a functional neutral active hyaluronidase domain. Included are modified amino-terminal leader peptides that enhance secretion of sHASEGP. The invention further comprises sialated and pegylated forms of a recombinant sHASEGP to enhance stability and serum pharmacokinetics over naturally occurring slaughterhouse enzymes. Further described are suitable formulations of a substantially purified recombinant sHASEGP glycoprotein derived from a eukaryotic cell that generate the proper glycosylation required for its optimal activity.
Inventor(s): Bookbinder; Louis H. (San Diego, CA), Kundu; Anirban (San Diego, CA), Frost; Gregory I. (Del Mar, CA)
Assignee: Halozyme, Inc. (San Diego, CA)
Application Number:10/795,095
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,767,429
Patent Claim Types:
see list of patent claims
Compound; Composition; Use; Formulation; Delivery; Dosage form; Device;

Drugs Protected by US Patent 7,767,429

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Halozyme Therap HYLENEX RECOMBINANT hyaluronidase recombinant human INJECTABLE;INJECTION 021859-001 Dec 2, 2005 RX Yes Yes ➤ Sign Up ➤ Sign Up Y Y ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 7,767,429

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,431,380 Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof ➤ Sign Up
9,211,315 Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases ➤ Sign Up
7,846,431 Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases ➤ Sign Up
9,677,062 Hyaluronidase and factor VIII compositions ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Mallinckrodt
UBS
Accenture
Teva
Moodys
Federal Trade Commission
Medtronic
US Army
Harvard Business School

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