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Serving hundreds of leading biopharmaceutical companies globally:

Queensland Health
Johnson and Johnson
Cantor Fitzgerald
Chubb
Mallinckrodt
Harvard Business School
Covington
McKesson
Citi

Generated: April 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 7,642,258

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Which drugs does patent 7,642,258 protect, and when does it expire?

Patent 7,642,258 protects COMBIGAN and is included in one NDA.

This patent has twenty-two patent family members in nineteen countries.
Summary for Patent: 7,642,258
Title:Combination of brimonidine and timolol for topical ophthalmic use
Abstract:Disclosed are pharmaceutical compositions comprising brimondine and timolol for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for glaucoma and associated conditions such as elevated intraocular pressure in the eyes of humans.
Inventor(s): Chang; Chin-Ming (Tustin, CA), Beck; Gary J. (Fullerton, CA), Pratt; Cynthia C. (Mission Viejo, CA), Batoosingh; Amy L. (Mission Viejo, CA)
Assignee: Allergan, Inc. (Irvine, CA)
Application Number:11/844,476
Patent Claim Types:
see list of patent claims
Composition; Use; Dosage form;

Drugs Protected by US Patent 7,642,258

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Allergan COMBIGAN brimonidine tartrate; timolol maleate SOLUTION/DROPS;OPHTHALMIC 021398-001 Oct 30, 2007 RX Yes Yes ➤ Sign Up ➤ Sign Up Y Y REDUCTION OF ELEVATED INTRAOCULAR PRESSURE IN PATIENTS WITH GLAUCOMA OR OCULAR HYPERTENSION WHO REQUIRE ADJUNCTIVE OR REPLACEMENT THERAPY DUE TO INADEQUATELY CONTROLLED IOP ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 7,642,258

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
7,323,463 Combination of brimonidine and timolol for topical ophthalmic use ➤ Sign Up
8,133,890 Combination of brimonidine and timolol for topical ophthalmic use ➤ Sign Up
8,354,409 Combination of brimonidine and timolol for topical ophthalmic use ➤ Sign Up
7,030,149 Combination of brimonidine timolol for topical ophthalmic use ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
Teva
Merck
Moodys
Cantor Fitzgerald
Fuji
QuintilesIMS
Cipla
Daiichi Sankyo

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