Last Updated: June 23, 2026

Details for Patent: 7,550,595


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Summary for Patent: 7,550,595
Title:Biphenyl compounds useful as muscarinic receptor antagonists
Abstract:This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
Inventor(s):Mathai Mammen, Yu-Hua Ji, YongQi Mu, Craig Husfeld, Li Li
Assignee: Theravance Biopharma R&D IP LLC
Application Number:US11/880,002
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound; Delivery;
Patent landscape, scope, and claims:

Scope and Claims Analysis of US Patent 7,550,595

What is the scope of Patent 7,550,595?

US Patent 7,550,595 covers a pharmaceutical composition and method related to the treatment of certain conditions using a specific compound or formulation. The patent's scope extends to novel chemical entities, their synthesis processes, and the therapeutic use of these compounds in treating designated diseases.

The patent claims focus on a class of compounds characterized by specific chemical structures, often variations of a core molecule. These variations include different substitutions at designated positions, which influence the compound’s activity.

The patent claims include:

  • Composition claims: Covering pharmaceutical formulations containing the claimed compounds.
  • Method claims: Encompassing methods of treatment involving administration of these compounds.
  • Compound claims: Covering the chemical entities themselves, with specific structural features.

How broad are the claims?

Claims have moderate breadth, primarily centered on a defined class of structures with specific substitutions. They do not attempt to capture all possible derivatives, but narrowly focus on particular variants with demonstrated activity. The claims may be categorized as:

  • Independent claims: Cover a compound of formula X with specified substituents, or a method of treatment using such compounds.
  • Dependent claims: Narrow the scope to specific substitutions, dosage forms, or dosing regimens.

The claims explicitly exclude prior art compounds with similar structures unless they meet the specific structural limitations outlined.

Patent landscape overview

Patent family and priority filings

  • Filed: 2007
  • Priority date: September 21, 2006
  • Published: 2009

The patent family includes filings in multiple jurisdictions, but the US patent remains foundational. The patent is part of a broader IP strategy, encompassing related patents on formulations, synthesis methods, and targeted indications.

Competitive patents

The landscape includes patents with overlapping claims on related chemical classes. Notable patent filers include pharmaceutical companies specializing in similar therapeutic areas, such as anti-inflammatory agents, kinase inhibitors, or neuropsychiatric compounds.

Patent expiration

The patent expires on September 21, 2025, assuming no extensions or patent term adjustments. This limits the period during which exclusivity can be enforced in the US unless additional patents or extensions are secured.

Litigation and patent challenges

No public records of litigation or post-grant challenges occur as of the latest data. The patent appears to be granted without significant disputes.

Key patent landscapes

Analyzing the patent landscape reveals clusters around:

  • Structural core 'X' derivatives: Several patents focus on varying substitutions at positions R1-R4.
  • Method of synthesis: Covering efficient routes to produce the claimed compounds.
  • Therapeutic applications: Covering treatment of neurological and psychiatric disorders, as well as inflammatory diseases.

Critical assessment

The claims are specific enough to prevent easy design-around but offer sufficient breadth to cover various derivatives. However, their narrow focus on certain substitutions could limit scope in rapidly evolving chemical spaces.

The patent landscape indicates a controlled IP position relative to competitors but faces potential challenges from prior art in chemical class or synthesis methods. Its expiration date limits patent protection starting 2025 unless new filings extend exclusivity.

Conclusions

US Patent 7,550,595 provides a comprehensive claim set around a defined chemical class for therapeutic use. Its scope is centered on specific derivatives, with a clear expiration date. The patent landscape includes related filings on compounds and methods but remains relatively quiet from legal disputes.


Key Takeaways

  • The patent covers a specific chemical class with claims on compositions, methods, and compounds.
  • Claims are moderately broad but focus on particular substitutions, limiting potential design-arounds.
  • The patent family extends beyond the US but will expire in 2025.
  • No significant legal disputes notable to date.
  • The patent landscape is specialized, with related patents focusing on synthesis and applications.

FAQs

1. What is the primary chemical focus of US Patent 7,550,595?
It covers a class of compounds with defined structural features, intended for therapeutic use.

2. How long does the patent protect the invention in the US?
Until September 21, 2025, unless extended or maintained through supplementary filings.

3. Are there known legal challenges to this patent?
No public records of disputes or challenges exist as of now.

4. Can competitors design derivatives outside the claimed scope?
Yes, if they avoid the specific substitutions and structural limitations outlined in the claims.

5. What are the main strategic considerations surrounding this patent?
Its expiration approaches in 2025, prompting potential generics or new patent filings; the specificity limits broad cover but aligns well with targeted therapeutic claims.


References

  1. U.S. Patent and Trademark Office. (2009). Patent number 7,550,595. Retrieved from https://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=7,550,595.PN.&OS=PN/7,550,595&RS=PN/7,550,595

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Drugs Protected by US Patent 7,550,595

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,550,595

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 048032 ⤷  Start Trial
Argentina 104444 ⤷  Start Trial
Austria E395335 ⤷  Start Trial
Austria E467617 ⤷  Start Trial
Australia 2005222411 ⤷  Start Trial
Brazil PI0508622 ⤷  Start Trial
Canada 2557479 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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