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BioPharmaceutical Business Intelligence

  • Analyze global market entry opportunities
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Serving leading biopharmaceutical companies globally:

QuintilesIMS
Harvard Business School
Federal Trade Commission
Farmers Insurance
US Department of Justice
Accenture
Boehringer Ingelheim
Covington
Chinese Patent Office
Medtronic

Generated: December 15, 2017

DrugPatentWatch Database Preview

Details for Patent: 7,378,423

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Which drugs does patent 7,378,423 protect, and when does it expire?


Patent 7,378,423 protects MEKINIST and is included in one NDA.

This patent has forty-one patent family members in twenty-seven countries.

Summary for Patent: 7,378,423

Title:Pyrimidine compound and medical use thereof
Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] ##STR00001## wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.
Inventor(s): Kawasaki; Hisashi (Osaka, JP), Abe; Hiroyuki (Osaka, JP), Hayakawa; Kazuhide (Osaka, JP), Iida; Tetsuya (Osaka, JP), Kikuchi; Shinichi (Osaka, JP), Yamaguchi; Takayuki (Osaka, JP), Nanayama; Toyomichi (Osaka, JP), Kurachi; Hironori (Osaka, JP), Tamaru; Masahiro (Osaka, JP), Hori; Yoshikazu (Osaka, JP), Takahashi; Mitsuru (Osaka, JP), Yoshida; Takayuki (Yokohama, JP), Sakai; Toshiyuki (Kyoto, JP)
Assignee: Japan Tobacco Inc. (Tokyo, JP)
Application Number:11/150,792
Patent Claim Types:
see list of patent claims
Compound; Composition;

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Patent Submitted Product Substance Delist Req. Patented / Exclusive Use
Novartis Pharms CorpMEKINISTtrametinib dimethyl sulfoxideTABLET;ORAL204114-001May 29, 2013RXYesNo► Subscribe► Subscribe► SubscribeYY
Novartis Pharms CorpMEKINISTtrametinib dimethyl sulfoxideTABLET;ORAL204114-002May 29, 2013DISCNYesNo► Subscribe► Subscribe► SubscribeYY
Novartis Pharms CorpMEKINISTtrametinib dimethyl sulfoxideTABLET;ORAL204114-003May 29, 2013RXYesYes► Subscribe► Subscribe► SubscribeYY
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Foreign Priority and PCT Information for Patent: 7,378,423

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2004-174770Jun 11, 2004
Japan2004-327111Nov 10, 2004

Non-Orange Book Patents for Patent: 7,378,423

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,835,443Pyrimidine compound and medical use thereof► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 7,378,423

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Russian Federation2364596► Subscribe
Russian Federation2007101158► Subscribe
Serbia52670► Subscribe
Serbia50569► Subscribe
Portugal2298768► Subscribe
Portugal1761528► Subscribe
New Zealand552090► Subscribe
Norway2016021► Subscribe
Norway338355► Subscribe
Norway20070155► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

US Army
Daiichi Sankyo
QuintilesIMS
Chinese Patent Office
Teva
Medtronic
McKinsey
Moodys
Harvard Business School
Fish and Richardson

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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