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|Title:||Solid dispersion pharamaceutical formulations|
|Abstract:||A pharmaceutical composition is disclosed which comprises a solid dispersion of an HIV protease inhibitor in a water soluble carrier, such as PEG, having enhanced bioavailability and improved dissolution properties. The solid dispersion may optionally be encapsulated in hard gelatin capsules, compressed into a tablet, or may be granulated with a pharmaceutically acceptable granulating agent. Also disclosed are methods of making said solid dispersion and methods of treating an HIV infection employing said solid dispersion.|
|Inventor(s):||Fort; James J. (Midlothian, VA), Krill; Steven L. (Chatham, NJ), Law; Devalina (Libertyville, IL), Qiu; Yihong (Gurnee, IL), Porter; William R. (Vernon Hills, IL), Schmitt; Eric A. (Libertyville, IL)|
|Assignee:||Abbott Laboratories (Abbott Park, IL)|
Patent Claim Types:|
see list of patent claims
|Composition; Dosage form; Delivery; Use;|
Field: Organic fine chemistry
Back Citations: 132nd percentile
Forward Citations: 5th percentile
|Applicant||Tradename||Generic Name||Dosage||NDA||Approval Date||Type||RLD||RS||Patent No.||Patent Expiration||Product||Substance||Delist Req.||Patented / Exclusive Use|
VIEKIRA PAK (COPACKAGED)
dasabuvir sodium ; ombitasvir; paritaprevir; ritonavir
|TABLET, TABLET;ORAL||206619-001||Dec 19, 2014||RX||Yes||Yes||7,364,752||► subscribe||Y|
dasabuvir sodium; ombitasvir; paritaprevir; ritonavir
|TABLET, EXTENDED RELEASE;ORAL||208624-001||Jul 22, 2016||RX||Yes||Yes||7,364,752||► subscribe||Y|
|TABLET;ORAL||021906-002||Nov 9, 2007||RX||Yes||No||7,364,752*PED||► subscribe||Y|
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