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|Abstract:||This invention provides a topical composition, in the form of an emulsion, that comprises a compound of the FK506 class; a physiologically acceptable alkanediol, ether diol or diether alcohol containing up to 8 carbon atoms as solvent for the compound of the FK506 class; an unsaturated fatty alcohol and water. In another aspect, this invention provides a topical pharmaceutical composition that comprises a macrolide in suspension. In a further aspect, this invention provides the use of an unsaturated fatty alcohol to stabilize a macrolide in a pharmaceutical composition.|
|Inventor(s):||Jackman; Martin (Allschwil, CH), Popp; Xue-Ping (Basel, CH), Richter; Friedrich (Grenzach-Wyhlen, DE), Schmook; Fritz (Vienna, AT)|
|Assignee:||Novartis AG (Basel, CH)|
Patent Claim Types:|
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