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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Farmers Insurance
UBS
McKesson
Citi
Daiichi Sankyo
US Department of Justice
Johnson and Johnson
Merck

Generated: May 27, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,165,497

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Summary for Patent: 6,165,497
Title: Subsaturated nicotine transdermal therapeutic system
Abstract:Rate controlled transdermal nicotine delivery systems are disclosed which utilize an in-line adhesive to maintain the systems on the skin. The initial equilibrated concentration of nicotine in the nicotine reservoir and the adhesive is below saturation, preferably at a thermodynamic activity no greater than 0.50, and the reservoir comprises the nicotine dissolved in a polymer with respect to which the rate controlling element of the device is substantially impermeable. In preferred embodiments the initial loading of nicotine in the reservoir is sufficient to prevent the activity of the nicotine in the reservoir from decreasing by more than about 75% and preferably no more than about 25% during the predetermined period of administration; and the thicknesses of the adhesive, rate controlling membrane and reservoir layers are selected so that at least 50% and, preferably at least 75% initial equilibrated nicotine loading is in the reservoir layer.
Inventor(s): Osborne; James L. (Mountain View, CA), Nelson; Melinda (Sunnyvale, CA), Enscore; David J. (Saratoga, CA), Yum; Su Il (Los Altos, CA), Gale; Robert M. (Los Altos, CA)
Assignee: ALZA Corporation (Mountain View, CA)
Application Number:07/662,857
Patent Claim Types:
see list of patent claims
Device; Use;

Drugs Protected by US Patent 6,165,497

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Family Members for US Patent 6,165,497

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Ireland 81102 ➤ Try a Free Trial
Australia 3852189 ➤ Try a Free Trial
Australia 3913695 ➤ Try a Free Trial
Australia 8585291 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

AstraZeneca
Farmers Insurance
Covington
Julphar
McKinsey
Cipla
Johnson and Johnson
Healthtrust
McKesson

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