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Serving leading biopharmaceutical companies globally:

US Department of Justice
Argus Health
Johnson and Johnson
Cantor Fitzgerald

Generated: December 15, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,912,015

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Summary for Patent: 5,912,015

Title: Modulated release from biocompatible polymers
Abstract:The present invention relates to a composition for the modulated release of a biologically active agent. The composition comprises a biocompatible polymeric matrix, a biologically active agent which is dispersed within the polymeric matrix, and a metal cation component which is separately dispersed within the polymeric matrix, whereby the metal cation component modulates the release of the biologically active agent from the polymeric matrix. The present invention also relates to a method for modulating the release of a biologically active agent from a biocompatible polymeric matrix, comprising the steps of dissolving a biocompatible polymer in a solvent to form a polymer solution and also separately dispersing a metal cation component and a biologically active agent within the polymer solution. The polymer solution is then solidified to form a polymeric matrix, wherein at least a significant portion of the metal cation component is dispersed in the polymeric matrix separately from the biologically active protein, and whereby the metal cation component modulates the release of the biologically active agent from the polymeric matrix.
Inventor(s): Bernstein; Howard (Cambridge, MA), Zhang; Yan (Belmont, CA), Khan; M. Amin (Carmel, IN), Tracy; Mark A. (Arlington, MA)
Assignee: Alkermes Controlled Therapeutics, Inc. (Cambridge, MA)
Application Number:09/056,566
Patent Claim Types:
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Use; Composition; Delivery;

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International Patent Family for Patent: 5,912,015

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia7187898► Subscribe
Canada2129514► Subscribe
Australia688506► Subscribe
Australia704647► Subscribe
Canada2189254► Subscribe
Germany69311538► Subscribe
Germany69532444► Subscribe
European Patent Office0630234► Subscribe
Australia668384► Subscribe
European Patent Office0758227► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Farmers Insurance
US Army
Express Scripts
Queensland Health

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