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Generated: August 19, 2017

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Title: Pharmaceutical compositions of conjugated estrogens and methods for their use
Abstract:This invention relates to novel pharmaceutical compositions and methods for their preparation containing conjugated estrogens for the treatment of peri-menopausal, menopausal and post-menopausal disorders in women. The novel pharmaceutical compositions comprise a carrier base material and conjugated estrogens formed into a solid unit dosage form possessing a regular incremental release of the medicament upon oral administration. Further, the invention comprises the combination of conjugated estrogens with progestogens in a solid, shaped dosage unit. Specifically, the invention comprises the use of an organic excipient such as high molecular weight hydroxyalkyl alkylcelluloses. The use of an organic excipient such as hydroxypropylmethylcellulose in a stable, solid dosage formulation containing either conjugated estrogens alone or in combination with a progestogen is described.
Inventor(s): Huber; Harold Eugene (Cincinnati, OH), Ryan; Mary Katherine (Mainville, OH)
Assignee: Duramed Pharmaceuticals, Inc. (Cincinnati, OH)
Application Number:08/690,407
Patent Claim Types:
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Use; Composition; Dosage form;

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Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria401062► Subscribe
Canada2227887► Subscribe
China100421652► Subscribe
China1197387► Subscribe
Germany69637601► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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