|Title:||Pharmaceutical compositions of conjugated estrogens and methods for their use|
|Abstract:||This invention relates to novel pharmaceutical compositions and methods for their preparation containing conjugated estrogens for the treatment of peri-menopausal, menopausal and post-menopausal disorders in women. The novel pharmaceutical compositions comprise a carrier base material and conjugated estrogens formed into a solid unit dosage form possessing a regular incremental release of the medicament upon oral administration. Further, the invention comprises the combination of conjugated estrogens with progestogens in a solid, shaped dosage unit. Specifically, the invention comprises the use of an organic excipient such as high molecular weight hydroxyalkyl alkylcelluloses. The use of an organic excipient such as hydroxypropylmethylcellulose in a stable, solid dosage formulation containing either conjugated estrogens alone or in combination with a progestogen is described.|
|Inventor(s):||Huber; Harold Eugene (Cincinnati, OH), Ryan; Mary Katherine (Mainville, OH)|
|Assignee:||Duramed Pharmaceuticals, Inc. (Cincinnati, OH)|
Patent Claim Types:|
see list of patent claims
|Use; Composition; Dosage form;|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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