Details for Patent: 5,861,379
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Summary for Patent: 5,861,379
Title: | Chimeric fatty body-pro-GRF analogs with increased biological potency |
Abstract: | The present invention relates to chimeric fatty body-pro-GRF analogs with increased biological potency, their application as anabolic agents and in the diagnosis and treatment of growth hormone deficiencies. The chimeric fatty body-pro-GRF analogs include an hydrophobic moiety (tail), and can be prepared, either by anchoring one or several hydrophobic tails to the GRF, or by substituting one or several amino-acids by a pseudomicellar residue in the chemical synthesis of GRF. The GRF analogs of the present invention are biodegradable, non-immunogenic and exhibit an improved anabolic potency with a reduced dosage and prolonged activity. |
Inventor(s): | Ibea; Michel (Montreal, CA), Abribat; Thierry (Montreal, CA), Brazeau; Paul (Montreal, CA) |
Assignee: | Theratechnologies Inc. (Montreal, CA) |
Application Number: | 08/702,114 |
Patent Claim Types: see list of patent claims | Compound; Composition; Formulation; Use; |
Drugs Protected by US Patent 5,861,379
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International Family Members for US Patent 5,861,379
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 204881 | See Plans and Pricing | |||
Austria | 311453 | See Plans and Pricing | |||
Australia | 5500799 | See Plans and Pricing | |||
Australia | 5683396 | See Plans and Pricing | |||
Australia | 697119 | See Plans and Pricing | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |