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Serving leading biopharmaceutical companies globally:

Julphar
Dow
Novartis
Harvard Business School
AstraZeneca
Boehringer Ingelheim
Johnson and Johnson
Queensland Health
Cerilliant
Daiichi Sankyo

Generated: January 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,773,001

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Summary for Patent: 5,773,001
Title: Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
Abstract:This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.
Inventor(s): Hamann; Philip Ross (Garnerville, NY), Hinman; Lois (N. Tarrytown, NY), Hollander; Irwin (Monsey, NY), Holcomb; Ryan (Glen Rock, NJ), Hallett; William (New City, NY), Tsou; Hwei-Ru (New City, NY), Weiss; Martin J. (Ft. Lee, NJ)
Assignee: American Cyanamid Company (Madison, NJ)
Application Number:08/253,877
Patent Claim Types:
see list of patent claims
Compound; Use; Composition; Formulation;

Drugs Protected by US Patent 5,773,001

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,773,001

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Israel 129953 ➤ Subscribe
Canada 2150785 ➤ Subscribe
Cyprus 2334 ➤ Subscribe
Germany 69528016 ➤ Subscribe
Denmark 0689845 ➤ Subscribe
European Patent Office 0689845 ➤ Subscribe
Spain 2181752 ➤ Subscribe
Finland 952720 ➤ Subscribe
Finland 117690 ➤ Subscribe
Israel 113984 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

McKinsey
Chinese Patent Office
Harvard Business School
Julphar
Baxter
QuintilesIMS
Colorcon
Federal Trade Commission
Healthtrust

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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