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Details for Patent: 5,720,938

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Summary for Patent: 5,720,938

Title: Systems for the formation of microbubbles
Abstract:A microbubble preparation formed of a plurality of microbubbles comprising a first gas and a second gas surrounded by a membrane such as a surfactant, wherein the first gas and the second gas are present in a molar ratio of from about 1:100 to about 1000:1, and wherein the first gas has a vapor pressure of at least about (760-x) mm Hg at 37.degree. C., where x is the vapor pressure of the second gas at 37.degree. C., and wherein the vapor pressure of each of the first and second gases is greater than about 75 mm Hg at 37.degree. C.; also disclosed are methods for preparing microbubble compositions, including compositions that rapidly shrink from a first average diameter to a second average diameter less than about 75% of the first average diameter and are stabilized at the second average diameter; methods and kits for preparing microbubbles; and methods for using such microbubbles as contrast agents.
Inventor(s): Schutt; Ernest G. (San Diego, CA), Anderson; Charles David (Lebanon, NJ), Evitts; David P. (La Jolla, CA)
Assignee: Alliance Pharmaceutical Corp. (San Diego, CA)
Application Number:08/476,079
Patent Claim Types:
see list of patent claims
Delivery; Compound; Device;

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Premature patent expiration for: 5,720,938

Expiration due to failure to pay maintenance fee

Patent Number Expiration Date
5,720,938 February 24, 2010

International Patent Family for Patent: 5,720,938

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria281183► subscribe
Australia4922196► subscribe
Australia5199701► subscribe
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