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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Colorcon
Julphar
Daiichi Sankyo
Cipla
Accenture
QuintilesIMS
McKinsey
Chubb

Generated: June 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,635,517

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Summary for Patent: 5,635,517
Title: Method of reducing TNF.alpha. levels with amino substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxo-and 1,3-dioxoisoindolines
Abstract:1-Oxo- and 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl) isoindolines substituted with amino in the benzo ring reduce the levels of TNF.alpha. in a mammal. A typical embodiment is 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline.
Inventor(s): Muller; George W. (Bridgewater, NJ), Stirling; David I. (Branchburg, NJ), Chen; Roger S. -C. (Edison, NJ)
Assignee: Celgene Corporation (Warren, NJ)
Application Number:08/690,258
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 5,635,517
Patent Claim Types:
see list of patent claims
Use; Compound;

Drugs Protected by US Patent 5,635,517

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Celgene REVLIMID lenalidomide CAPSULE;ORAL 021880-005 Dec 21, 2011 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Celgene REVLIMID lenalidomide CAPSULE;ORAL 021880-001 Dec 27, 2005 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Celgene REVLIMID lenalidomide CAPSULE;ORAL 021880-002 Dec 27, 2005 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Celgene REVLIMID lenalidomide CAPSULE;ORAL 021880-003 Jun 29, 2006 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 5,635,517

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,335,349 Substituted 2(2,6-dioxopiperidin-3-yl)isoindolines ➤ Try a Free Trial
6,476,052 Isoindolines, method of use, and pharmaceutical compositions ➤ Try a Free Trial
6,555,554 Isoindolines, method of use, and pharmaceutical compositions ➤ Try a Free Trial
5,798,368 Tetrasubstituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines and method of reducing TNF.alpha. levels ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Family Members for US Patent 5,635,517

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 229521 ➤ Try a Free Trial
Austria 275139 ➤ Try a Free Trial
Austria 401319 ➤ Try a Free Trial
Austria 460409 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Farmers Insurance
Merck
Deloitte
Colorcon
Federal Trade Commission
Daiichi Sankyo
Fish and Richardson
UBS

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