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Serving hundreds of leading biopharmaceutical companies globally:

Moodys
Daiichi Sankyo
QuintilesIMS
Chubb
Covington
Medtronic
Express Scripts
Johnson and Johnson
McKinsey

Generated: June 24, 2018

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Details for Patent: 5,633,272

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Summary for Patent: 5,633,272
Title: Substituted isoxazoles for the treatment of inflammation
Abstract:A class of substituted isoxazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II ##STR1## wherein R.sup.1 is selected from hydroxyl, lower alkyl, carboxyl, lower carboxyalkyl, lower aminocarbonylalkyl, lower alkoxycarbonylalkyl, lower aralkyl, lower alkoxyalkyl, lower aralkoxyalkyl, lower alkylthioalkyl, lower aralkylthioalkyl, lower alkylaminoalkyl, lower aryloxyalkyl, lower arylthioalkyl, lower haloalkyl, lower hydroxylalkyl, cycloalkyl, cycloalkylalkyl, and aralkyl; wherein R.sup.3 is selected from cycloalkyl, cycloalkenyl, aryl, and heteroaryl; wherein R.sup.3 is optionally substituted at a substitutable position with one or more radicals independently selected from lower alkylsulfinyl, lower alkyl, cyano, carboxyl, lower alkoxycarbonyl, lower haloalkyl, hydroxyl, lower hydroxyalkyl, lower haloalkoxy, amino, lower alkylamino, lower arylamino, lower aminoalkyl, nitro, halo, lower alkoxy, aminosulfonyl, and lower alkylthio; and wherein R.sup.4 is selected from lower alkyl, hydroxyl and amino; or a pharmaceutically-acceptable salt thereof.
Inventor(s): Talley; John J. (Brentwood, MO), Brown; David L. (Chesterfield, MO), Nagarajan; Srinivasan (Chesterfield, MO), Carter; Jeffery S. (Chesterfield, MO), Weier; Richard M. (Lake Bluff, IL), Stealey; Michael A. (Libertyville, IL), Collins; Paul W. (Deerfield, IL), Rogers, deceased; Roland S. (late of Richmond Heights, MO), Seibert; Karen (St. Louis, MO)
Assignee:
Application Number:08/473,884
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 5,633,272
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

Drugs Protected by US Patent 5,633,272

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Family Members for US Patent 5,633,272

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 223390 ➤ Try a Free Trial
Australia 4867196 ➤ Try a Free Trial
Australia 699593 ➤ Try a Free Trial
Brazil 9607035 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Moodys
Chubb
QuintilesIMS
Cipla
UBS
Queensland Health
Johnson and Johnson
Argus Health
Daiichi Sankyo

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