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Serving leading biopharmaceutical companies globally:

Fish and Richardson
Boehringer Ingelheim
Daiichi Sankyo

Generated: October 24, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,633,272

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Summary for Patent: 5,633,272

Title: Substituted isoxazoles for the treatment of inflammation
Abstract:A class of substituted isoxazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II ##STR1## wherein R.sup.1 is selected from hydroxyl, lower alkyl, carboxyl, lower carboxyalkyl, lower aminocarbonylalkyl, lower alkoxycarbonylalkyl, lower aralkyl, lower alkoxyalkyl, lower aralkoxyalkyl, lower alkylthioalkyl, lower aralkylthioalkyl, lower alkylaminoalkyl, lower aryloxyalkyl, lower arylthioalkyl, lower haloalkyl, lower hydroxylalkyl, cycloalkyl, cycloalkylalkyl, and aralkyl; wherein R.sup.3 is selected from cycloalkyl, cycloalkenyl, aryl, and heteroaryl; wherein R.sup.3 is optionally substituted at a substitutable position with one or more radicals independently selected from lower alkylsulfinyl, lower alkyl, cyano, carboxyl, lower alkoxycarbonyl, lower haloalkyl, hydroxyl, lower hydroxyalkyl, lower haloalkoxy, amino, lower alkylamino, lower arylamino, lower aminoalkyl, nitro, halo, lower alkoxy, aminosulfonyl, and lower alkylthio; and wherein R.sup.4 is selected from lower alkyl, hydroxyl and amino; or a pharmaceutically-acceptable salt thereof.
Inventor(s): Talley; John J. (Brentwood, MO), Brown; David L. (Chesterfield, MO), Nagarajan; Srinivasan (Chesterfield, MO), Carter; Jeffery S. (Chesterfield, MO), Weier; Richard M. (Lake Bluff, IL), Stealey; Michael A. (Libertyville, IL), Collins; Paul W. (Deerfield, IL), Rogers, deceased; Roland S. (late of Richmond Heights, MO), Seibert; Karen (St. Louis, MO)
Application Number:08/473,884
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

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International Patent Family for Patent: 5,633,272

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria223390► Subscribe
Australia4867196► Subscribe
Australia699593► Subscribe
Brazil9607035► Subscribe
Canada2212836► Subscribe
China1107058► Subscribe
China1181075► Subscribe
China1214790► Subscribe
China1442139► Subscribe
Czech Republic293211► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Chinese Patent Office
Queensland Health

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