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Details for Patent: 5,599,794

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Summary for Patent: 5,599,794

Title: Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic
Abstract:The invention consists of a combination of a substance that increases the intragastric pH and an acid degradable antibacterial compound. By this combined product regimen it will be possible to obtain maximal local antibacterial effect of acid degradable antibiotics as well as enhanced bioavailability of the active antibiotic, thus resulting in higher amounts of the active compound in the gastric mucosa due to secretion of weak bases. Both pharmacological effects contribute to drastically increased antimicrobial capacity of acid degradable antibiotics to be used against local infections in the gastrointestinal tract causing gastritis and/or peptic ulcer. The invention also selects to the use of said combination and a process for the preparation thereof.
Inventor(s): Eek; Arne T. (Trosa, SE), Sj ostrand; Sven Erik (S odert alje, SE)
Assignee: Aktiebolaget Astra (Sodertalje, SE)
Application Number:08/051,722
Patent Claim Types:
see list of patent claims
Use; Compound;

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Premature patent expiration for: 5,599,794

Expiration due to failure to pay maintenance fee

Patent Number Expiration Date
5,599,794 February 04, 2005

Foreign Priority and PCT Information for Patent: 5,599,794

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Sweden9201297Apr 24, 1992
Sweden9300029Jan 08, 1993

International Patent Family for Patent: 5,599,794

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO)466► subscribe
African Regional IP Organization (ARIPO)9300518► subscribe
Austria194286► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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