Generated: December 17, 2017
DrugPatentWatch Database Preview
Details for Patent: 5,585,397
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Summary for Patent: 5,585,397
|Title:|| Sulfonamide inhibitors of aspartyl protease|
|Abstract:||The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.|
|Inventor(s):|| Tung; Roger D. (Arlington, MA), Murcko; Mark A. (Holliston, MA), Bhisetti; Govinda R. (Lexington, MA) |
|Assignee:|| Vertex Pharmaceuticals, Incorporated (Cambridge, MA) |
Patent Claim Types:|
see list of patent claims
|Compound; Composition; |
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Foreign Priority and PCT Information for Patent: 5,585,397
|PCT Filed||September 07, 1993||PCT Application Number:||PCT/US93/08458|
|PCT Publication Date:||March 17, 1994||PCT Publication Number:||
International Patent Family for Patent: 5,585,397
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