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Serving hundreds of leading biopharmaceutical companies globally:

Cerilliant
Farmers Insurance
Chubb
US Army
Harvard Business School
Dow
Healthtrust
Medtronic
Cantor Fitzgerald

Generated: May 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,585,397

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Summary for Patent: 5,585,397
Title: Sulfonamide inhibitors of aspartyl protease
Abstract:The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.
Inventor(s): Tung; Roger D. (Arlington, MA), Murcko; Mark A. (Holliston, MA), Bhisetti; Govinda R. (Lexington, MA)
Assignee: Vertex Pharmaceuticals, Incorporated (Cambridge, MA)
Application Number:08/142,327
Patent Claim Types:
see list of patent claims
Compound; Composition;

Drugs Protected by US Patent 5,585,397

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,585,397

PCT Information
PCT FiledSeptember 07, 1993PCT Application Number:PCT/US93/08458
PCT Publication Date:March 17, 1994PCT Publication Number: WO94/05639

International Family Members for US Patent 5,585,397

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Hungary 224027 ➤ Try a Free Trial
China 1061339 ➤ Try a Free Trial
China 1181755 ➤ Try a Free Trial
Colombia 4870779 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
Express Scripts
AstraZeneca
Cerilliant
Daiichi Sankyo
UBS
Boehringer Ingelheim
Fuji
Queensland Health

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