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Serving hundreds of leading biopharmaceutical companies globally:

Moodys
Dow
Harvard Business School
Daiichi Sankyo
UBS
Cantor Fitzgerald
Queensland Health
Express Scripts
US Army

Generated: April 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,504,207

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Summary for Patent: 5,504,207
Title: Process and intermediate for the preparation of terazosin hydrochloride dihydrate
Abstract:A process for the preparation of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride (terazosin hydrochloride dihydrate comprises the steps of reacting 4-amino-2-chloro-6,7-dimethoxy-quinazoline with N-(2-tetrahydrofuroyl)piperazine in an anhydrous polar organic solvent in the absence of an added acid scavenger to produce anhydrous 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride (Form IV) and thereafter converting the product of that step to 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine hydrochloride dihydrate.
Inventor(s): Mannino; Anthony (Round Lake Beach, IL), Henry; Rodger F. (Waukegan, IL), Heitmann; Wayne R. (Lindenhurst, IL), Horrom; Bruce W. (Waukegan, IL)
Assignee: Abbott Laboratories (Abbott Park, IL)
Application Number:08/324,635
Patent Claim Types:
see list of patent claims
Compound; Process;

Drugs Protected by US Patent 5,504,207

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

Johnson and Johnson
Chubb
US Department of Justice
Merck
Covington
Teva
Baxter
Cerilliant
Federal Trade Commission

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