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Serving hundreds of leading biopharmaceutical companies globally:

AstraZeneca
Daiichi Sankyo
Chubb
Cantor Fitzgerald
US Army
Mallinckrodt
McKesson
Healthtrust
Accenture

Generated: June 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,504,207

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Summary for Patent: 5,504,207
Title: Process and intermediate for the preparation of terazosin hydrochloride dihydrate
Abstract:A process for the preparation of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride (terazosin hydrochloride dihydrate comprises the steps of reacting 4-amino-2-chloro-6,7-dimethoxy-quinazoline with N-(2-tetrahydrofuroyl)piperazine in an anhydrous polar organic solvent in the absence of an added acid scavenger to produce anhydrous 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride (Form IV) and thereafter converting the product of that step to 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine hydrochloride dihydrate.
Inventor(s): Mannino; Anthony (Round Lake Beach, IL), Henry; Rodger F. (Waukegan, IL), Heitmann; Wayne R. (Lindenhurst, IL), Horrom; Bruce W. (Waukegan, IL)
Assignee: Abbott Laboratories (Abbott Park, IL)
Application Number:08/324,635
Patent Claim Types:
see list of patent claims
Compound; Process;

Drugs Protected by US Patent 5,504,207

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Family Members for US Patent 5,504,207

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 143959 ➤ Try a Free Trial
Brazil 1100705 ➤ Try a Free Trial
Canada 2143971 ➤ Try a Free Trial
Germany 69500064 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

US Army
AstraZeneca
Citi
Deloitte
Medtronic
McKesson
Queensland Health
Dow
Chubb

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