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Details for Patent: 5,466,861

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Summary for Patent: 5,466,861

Title: Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
Abstract:Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and n are as defined herein. The novel compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well.
Inventor(s): Dawson; Marcia L. (Menlo Park, CA), Cameron; James F. (Palo Alto, CA), Hobbs; Peter D. (Moss Beach, CA), Jong; Ling (Sunnyvale, CA), Pfahl; Magnus (Solana Beach, CA), Zhang; Xiao-kun (La Jolla, CA), Lehmann; Jurgen M. (Solana Beach, CA)
Assignee: SRI International (Menlo Park, CA) La Jolla Cancer Research Foundation (La Jolla, CA)
Application Number:07/982,305
Patent Claim Types:
see list of patent claims
Compound; Composition;

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International Patent Family for Patent: 5,466,861

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Japan2007001982► subscribe
Brazil9307528► subscribe
Canada2149882► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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