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Last Updated: December 14, 2025

Claims for Patent: 5,466,861


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Summary for Patent: 5,466,861
Title:Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
Abstract:Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R1, R2, R3, R4, R5 and n are as defined herein. The novel compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well.
Inventor(s):Marcia L. Dawson, James F. Cameron, Peter D. Hobbs, Ling Jong, Magnus Pfahl, Xiao-kun Zhang, Jurgen M. Lehmann
Assignee:Ligand Pharmaceuticals Inc
Application Number:US07/982,305
Patent Claims:

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