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Serving leading biopharmaceutical companies globally:

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Merck
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Express Scripts
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Generated: February 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,466,810

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Summary for Patent: 5,466,810
Title: 2-amino-3-aroyl-benzo[.beta.]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)-benzoyl]benzo[.beta.] thiophenes
Abstract:A group of 2-amino-3-aroyl-benzo[.beta.]thiophenes are prepared by treating an aldehyde with an anion of dimethylamino thioformamide, cyclizing the .alpha.-hydroxy thioamide, and subsequently acylating the benzo[.beta.]thiophene to yield the 2-amino-3-aryl derivative. These compounds may be treated with suitable phenyl Grignard reagents, and after deprotection, yield 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[.beta .]thiophene.
Inventor(s): Godfrey; Alexander G. (Greenwood, IN)
Assignee: Eli Lilly and Company (Indianapolis, IN)
Application Number:08/257,859
Patent Claim Types:
see list of patent claims
Compound;

Drugs Protected by US Patent 5,466,810

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,466,810

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 200671 ➤ Sign Up
Australia 2702995 ➤ Sign Up
Brazil 9507956 ➤ Sign Up
Canada 2192097 ➤ Sign Up
Germany 69520738 ➤ Sign Up
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European Patent Office 0765321 ➤ Sign Up
Spain 2155891 ➤ Sign Up
Finland 964914 ➤ Sign Up
Greece 3036028 ➤ Sign Up
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Chubb
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