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Serving hundreds of leading biopharmaceutical companies globally:

US Army
Cipla
Dow
Cantor Fitzgerald
UBS
Daiichi Sankyo
Citi
McKesson
Julphar

Generated: May 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,270,057

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Summary for Patent: 5,270,057
Title: Stabilized gonadotropin containing preparations
Abstract:Disclosed are lyophilized gonadotropin containing preparations containing a dicarboxylic acid salt stabilizer. The particular proteins (e.g. LH, TSH, FSH, or HCG) are in admixture with, and at least partially capable of stabilization by, the particular stabilizer in lyophilized form. The preparations contain a sufficient amount of dicarboxylic acid salt to stabilize the protein in freeze-dried form for a desired time at a desired temperature. Typical dicarboxylic acid salts disclosed are the salts of citric, tartaric, and aspartic acids. The preparations preferably include a non-reducing disaccharide to increase the collapse temperature of the solution to be lyophilized. Methods of making the preparations in lyophilized form and the resulting injectable preparations are also disclosed.
Inventor(s): de Meere; Andreas L. J. (Waspik, NL), De Ruiter; Marinus A. (Oss, NL)
Assignee: Akzo N.V. (Arnhem, NL)
Application Number:07/914,227
Patent Claim Types:
see list of patent claims
Composition; Formulation;

Drugs Protected by US Patent 5,270,057

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,270,057

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
90.200665.9Mar 20, 1990

International Family Members for US Patent 5,270,057

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada 2037884 ➤ Try a Free Trial
Germany 69102465 ➤ Try a Free Trial
Denmark 0448146 ➤ Try a Free Trial
European Patent Office 0448146 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Queensland Health
Federal Trade Commission
AstraZeneca
Accenture
Healthtrust
McKinsey
Teva
Medtronic
Cantor Fitzgerald

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