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|Title:||Transdermal therapeutic system comprising as active component buprenorphine|
|Abstract:||The controlled release of buprenorphine or the pharmaceutically acceptable salts thereof to the skin over a period of time of at least 24 hours is ensured by a transdermal therapeutic system consisting of a backing layer which is impermeable to the active substance, a pressure-sensitive adhesive reservoir layer, and optionally a removable protective layer. Said reservoir layer of said system comprises 20 to 90%-wt polymeric material, 0.1 to 30%-wt softener, 0.1 to 20%-wt buprenorphine base or one of the pharmaceutically acceptable salts thereof, and 0.1 to 30%-wt solvent for the active substance base.|
|Inventor(s):||Hille; Thomas (Neuwied, DE), Deurer; Lothar (Koblenz, DE), Hoffmann; Hans-Rainer (Neuwied, DE)|
|Assignee:||LTS Lohmann Therapie-Systeme GmbH & Co. KG (Neuwied, DE)|
Patent Claim Types:|
see list of patent claims
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Germany||3939376||Nov 29, 1989|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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