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Details for Patent: 5,179,189

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Summary for Patent: 5,179,189

Title: Fatty acid terminated polyanhydrides
Abstract:Fatty acid terminated polyanhydrides suitable for use as controlled release matrices in biodegradable sustained release drug delivery systems and methods for making thereof are described. The polymers are more soluble in organic solvents, and have a lower melting point than the corresponding non-fatty acid terminated polyanhydrides. The fatty acid terminated polyanhydrides are also more hydrophobic than the corresponding polyanhydrides that are not terminated with a fatty acid, and combine the properties of thermodynamic and hydrolytic stability, and easy storage. The polymers can be produced with a controlled and low molecular weight. The polyanhydrides are useful in a number of applications, including as a matrix in biodegradable drug delivery systems.
Inventor(s): Domb; Abraham J. (Baltimore, MD), Maniar; Manoj (Baltimore, MD)
Assignee: Nova Pharmaceutical Corporation (Baltimore, MD)
Application Number:07/756,483
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International Patent Family for Patent: 5,179,189

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada2073561<disabled in preview>
Canada2083161<disabled in preview>
Canada2118584<disabled in preview>
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